DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7963 and CG8159

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	90/370 - (24%)
Similarity:	144/370 - (38%)	Gaps:	86/370 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRVCLKQDELLVDIYEIVEEMQVDLCTLLETCG---GIKVDRRDVQPMYLCQECTNELLIAAKFR 71
            ||||...    .|..:.::......|.:|:...   |:.:......|.::|:.|..:|..|..||
  Fly     6 CRVCASS----TDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFR 66

  Fly    72 KICVESEKL----------------------------RDMAPEINIDTAEPLASEEIIIIDPSDY 108
            ..|:.|:|:                            .|.||:   ..|.||   |::|
  Fly    67 DRCLRSQKIFEESLVRNEEDTFRSSVRRSARSQRQRHEDTAPK---TPASPL---EVMI------ 119

  Fly   109 IEQLSAVEDPENEPIGVSRWNCQHCG-AGFQLS-EVLRRHIQEVHASITIIDCRERRRIFTKLGC 171
              :|.::.:.:.|..|:.  :...|. |..:|: :.:....::...:..:...|.|||...|.|
  Fly   120 --KLESLSNGDEEDDGID--HLDSCNEADMELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGG- 179

  Fly   172 YQVHNCSYAKTPKRGHKCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRR 236
             :..|.:....|.  ..|.:||..:...||...|:|.|:...||.|:.|...|.::|.|:.||..
  Fly   180 -KGENRTKVTLPV--FFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVM 241

  Fly   237 HKQVLQHKCLHCGRGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYA 301
            |....:.:|.:|.|.:|..|...|                             |.||:|.:||:.
  Fly   242 HTGDRKFQCRYCDRTYVNYSGRLR-----------------------------HERTHTNDRPFI 277

  Fly   302 CQHRDKRFAQLGVLKIHERIHTGERLHRCQVCEKPFTRAGQLRKH 346
            |....|.|....:||.|..|||||||.||::|.:.|.|...|:.|
  Fly   278 CAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKTH 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	17/72 (24%)
		C2H2 Zn finger	159..179	CDD:275368	7/19 (37%)
		COG5048	184..>250	CDD:227381	20/65 (31%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..262	CDD:275368	6/16 (38%)
		C2H2 Zn finger	274..294	CDD:275368	2/19 (11%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		zf-H2C2_2	315..339	CDD:290200	14/23 (61%)
		C2H2 Zn finger	330..350	CDD:275368	6/17 (35%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	18/75 (24%)
		C2H2 Zn finger	194..214	CDD:275368	7/19 (37%)
		COG5048	<197..322	CDD:227381	48/153 (31%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	8/48 (17%)
		zf-H2C2_2	265..287	CDD:290200	10/50 (20%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..315	CDD:290200	14/23 (61%)
		C2H2 Zn finger	306..328	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000