DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7963 and CG11696

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	350	Identity:	85/350 - (24%)
Similarity:	135/350 - (38%)	Gaps:	82/350 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VDIYEIVEEMQVDLCTLLETCGGIKVDRRDVQPMYLCQ-ECTNELLIAAKFRKICVESEKLRDMA 84
            :|.| |...:::| |.:   |.....|..|::..:..: :||.       :.|.|....|.|.:
  Fly   290 MDDY-IAANVKLD-CAI---CAAPLEDFNDLKRHFRVEHDCTG-------YVKCCNNRYKKRTL- 341

  Fly    85 PEINIDTAEPLASEEIIIIDPSDYIEQLSAVEDPENEPIGVSRWNCQHCGAGF-----QLSEVLR 144
                                   |::.|...:||:       .::||.|...|     |:..:||
  Fly   342 -----------------------YVDHLHCHKDPQ-------YFSCQSCRKNFLNRNSQVMHMLR 376

  Fly   145 RHIQEVHASITIIDCRERRRIFTKLGCYQVHNCSYAKTPKRGHK-------CLECGKCLQSASSL 202
            .|.|:.........|..|   |.|.....:|        .:|||       |..|.|..::...|
  Fly   377 FHSQQQELVHQCAICEAR---FAKKFLLTMH--------LKGHKGTERPEVCDTCSKTFRTKFEL 430

  Fly   203 ASHI-RLH-TDEWPFTCDQCAKAFRTNGALEVHQRR-HKQ--VLQHKCLHCGRGFVESSNLRRHI 262
            ::|: |:| .|..|..||.|...||:.....:|::. |..  |.:.:|..|||...:..:||:|:
  Fly   431 SAHVKRMHAADFTPIICDICGTHFRSKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHL 495

  Fly   263 VNRH------TEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERI 321
            . ||      |:.|..|||..:.|.:   .|..|:|.:...:.:.|...||.|.....|..|...
  Fly   496 A-RHDDRDGDTKYRCLLCNAEKSSRA---ALSSHMRYHHSAKRHKCSLCDKEFKLPRALAEHMAT 556

  Fly   322 HTGERLHRCQVCEKPFTRAGQLRKH 346
            |||..|::||.|.:.|.....:..|
  Fly   557 HTGIDLYQCQFCTRTFKSHANMHNH 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	12/59 (20%)
		C2H2 Zn finger	159..179	CDD:275368	5/19 (26%)
		COG5048	184..>250	CDD:227381	22/77 (29%)
		C2H2 Zn finger	189..209	CDD:275368	6/20 (30%)
		C2H2 Zn finger	217..237	CDD:275368	6/20 (30%)
		C2H2 Zn finger	245..262	CDD:275368	6/16 (38%)
		C2H2 Zn finger	274..294	CDD:275368	6/19 (32%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		zf-H2C2_2	315..339	CDD:290200	10/23 (43%)
		C2H2 Zn finger	330..350	CDD:275368	4/16 (25%)
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368	5/40 (13%)
		C2H2 Zn finger	357..378	CDD:275368	7/20 (35%)
		C2H2 Zn finger	388..408	CDD:275368	5/30 (17%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	447..465	CDD:275368	6/17 (35%)
		C2H2 Zn finger	478..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	509..529	CDD:275368	7/22 (32%)
		C2H2 Zn finger	537..557	CDD:275368	6/19 (32%)
		C2H2 Zn finger	565..583	CDD:275368	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000