DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7963 and klf-1

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_497632.1	Gene:	klf-1 / 175404	WormBaseID:	WBGene00018990	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	74/298 - (24%)
Similarity:	105/298 - (35%)	Gaps:	104/298 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CVESE----KLRDMAPEINIDTAEPLASEEIIIIDPSDYIEQLSAVED-PENEPIGVSRWNCQHC 133
            ||:..    .|||          |||...          :|.:|:..| |.:....|:.:..|:
Worm   282 CVKRSAMNFDLRD----------EPLTVN----------VESVSSTSDLPSSVSSSVNSFVYQN- 325

  Fly   134 GAGFQLSEVLRRHIQEVHASITII---DCR---ERRRIFTKLGC----YQVHNCSYAKTPKRGH- 187
               |...| .:|.|.|:.||..:.   |..   :...|.|:|..    .:.|....|:..:|.|
Worm   326 ---FDPLE-FKRKIDELTASACLAVMPDANGQVDPMAIKTQLDAIKKQMEEHQTHMAEASQRLHV 386

  Fly   188 -KCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKCLH--CG 249
             ..||...|..|.||                        :..|.|...:|     .|.|.|  ||
Worm   387 DSSLEDSNCEPSPSS------------------------SYDASEPSVKR-----LHHCTHPNCG 422

  Fly   250 RGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHR--DKRFAQL 312
            :.:.:||:|:                             .|.||:|||:||.|...  |.|||:.
Worm   423 KVYTKSSHLK-----------------------------AHFRTHTGEKPYECSWDGCDWRFARS 458

  Fly   313 GVLKIHERIHTGERLHRCQVCEKPFTRAGQLRKHALRH 350
            ..|..|.|.|||:|..:|..|.:.|:|:..|..|..||
Worm   459 DELTRHYRKHTGDRPFKCSQCSRAFSRSDHLSLHMKRH 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	2/9 (22%)
		C2H2 Zn finger	159..179	CDD:275368	4/26 (15%)
		COG5048	184..>250	CDD:227381	15/69 (22%)
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		C2H2 Zn finger	217..237	CDD:275368	2/19 (11%)
		C2H2 Zn finger	245..262	CDD:275368	7/18 (39%)
		C2H2 Zn finger	274..294	CDD:275368	2/19 (11%)
		C2H2 Zn finger	302..322	CDD:275368	8/21 (38%)
		zf-H2C2_2	315..339	CDD:290200	10/23 (43%)
		C2H2 Zn finger	330..350	CDD:275368	6/19 (32%)
klf-1	NP_497632.1	COG5048	398..>481	CDD:227381	36/140 (26%)
		C2H2 Zn finger	419..438	CDD:275368	7/47 (15%)
		zf-H2C2_2	430..457	CDD:290200	13/55 (24%)
		C2H2 Zn finger	446..468	CDD:275368	8/21 (38%)
		zf-H2C2_2	460..485	CDD:290200	10/24 (42%)
		C2H2 Zn finger	476..496	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000