DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7352 and mns1

DIOPT Version :9

Sequence 1:	NP_649795.1	Gene:	CG7352 / 40997	FlyBaseID:	FBgn0037581	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_009301508.1	Gene:	mns1 / 573382	ZFINID:	ZDB-GENE-030521-42	Length:	503	Species:	Danio rerio

Alignment Length:	465	Identity:	119/465 - (25%)
Similarity:	214/465 - (46%)	Gaps:	63/465 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QVPHSLRKEHDFFSSQLFRKLQYD-----LEEVSRSQELSKVSPITRDFIEEAAMTQEMQDLKRA 83
            |:..:|..|......:|.||||.:     :||.....|..|:.. .|...:|..|.:|:..:...
Zfish    41 QLEANLSCEDRIERKRLLRKLQDEEYGKQIEESLLRAEEDKLFR-ERQLEQEERMAKELARINNE 104

  Fly    84 EFVERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLE---AAEVSQERCL 145
            :..:.|.||.::.:..|||:|..:|:.|.::|:.|..:.||:..|...::.|   |..:..|..|
Zfish   105 KLRDEKMRQYIKENSVELRELELKLKSAYLNRERAAQMAEKEAMRYETLREEAMIARTMRDEHEL 169

  Fly   146 LEVRQREKEVALKEEQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELE 210
            .|:.:.:.|....||..|.::.|..|:||..|:|.:.:.:.:.::.:...:.::|..||: .||:
Zfish   170 AEMEKEKLEQKKYEEVVRYQQELERQLEEKERKRQEAYEEFLKEKHMVDEIVRKIYMEDQ-MELQ 233

  Fly   211 AQRKKLQKRQDMLRSIKENQELREWQRAQ------YNQELSDLVQKQSDMERRKLQLEAERQEIQ 269
            .|..|::..|..:...|:.|  .||:|.:      .|:.:.:..|.|...|..::   |:.:|.:
Zfish   234 LQLDKMKATQRYIEDFKKQQ--AEWRRMEREKVEAENRRIIEFAQYQQRKEEDRM---AKVRERE 293

  Fly   270 RKKQEISIRLGQQVLEIENKKRH-----RDNLLLDLLEAEYTAKSDERYRQQMQQEQMSRQRTRQ 329
            :.|:.:...|.:|: |:|.::|.     |:.|.|:        :..|..|||..:|...|.|.|.
Zfish   294 QAKETLHKMLSEQI-ELEKQQREKMERAREELCLE--------EQAEAARQQEIEEMEKRIRQRL 349

  Fly   330 ELDRYRQE-VKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNH 393
            ||.:.:|| :..:|:...:.|..|.|.||.........:..:|::..:||         |.:..|
Zfish   350 ELQQTQQEMMAFKKLRLQEEKEEEEAFRQTMMAKFAEDDRIEQMNAQKRR---------MKQLEH 405

  Fly   394 RKRAEATAE--NVQYFDMKAKIDAEQEER-------------IKQERLAMLSQVPSSVLRYLPKH 443
            ::..|...|  ..||.   |:.:.|::||             |::||..:|.|..:.:|.||||.
Zfish   406 KRAVEQLLEERRQQYL---AEQEREEQERAVELEREAQRRRIIEEERQRLLKQHATKLLGYLPKG 467

  Fly   444 VLKSTDREHF 453
            :.|..|.|||
Zfish   468 IFKEEDLEHF 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7352	NP_649795.1	TPH	97..439	CDD:290579	91/371 (25%)
mns1	XP_009301508.1	TPH	115..466	CDD:316391	93/377 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JVC
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51916
OrthoDB	1	1.010	-	-		D449210at33208
OrthoFinder	1	1.000	-	-		FOG0008162
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104986
Panther	1	1.100	-	-	LDO	PTHR19265
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920