Protein Alignment CG7352 and Mns1

DIOPT Version :10

• Sequence 1: NP_649795.1
• Gene: CG7352 / 40997
• FlyBaseID: FBgn0037581
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_001007753.1
• Gene: Mns1 / 363093
• RGDID: 1549718
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 438
• Identity: 118/438 - (26%)
• Similarity: 219/438 - (50%)
• Gaps: 60/438 - (13%)

  Fly    43 KLQYDLEE-VSRSQELSKVSPITRDFIEEAAMTQEMQDLKRAEFVERKRRQQLRRDCEELRDLAE 106
            :.:.|:|| |.:::|..::.  .|...:|..:..|:..||.....:.|.|||:|.:..|||:|.:
  Rat    64 QFELDMEEAVQKAEENKRMR--DRQLEQEERLANELARLKHESLKDEKMRQQVRENSIELRELEQ 126

  Fly   107 QLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQR-EKEVALKEEQRRLRES--- 167
            :|:.|.::::.|..:.||...:...:|.: ||:  ||.::|..:| .||..:|:|:|....:
  Rat   127 KLKAAYMNKERAAQIVEKDVIKYEQMKRD-AEI--ERIMMEEHKRLLKEENVKQEKRDKERAQYY 188

  Fly   168 --LAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQ 230
              |.:|:|:..||:.:.:.|::.::.:...:.::|.|||   :||.| :||:||..:.:.|||.|
  Rat   189 VDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEED---QLERQ-QKLEKRNAIQKYIKEFQ 249

  Fly   231 ELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDN 295
            ..::..|.:..:|:.:        |.||: ||..:.:.||:.:.::     :|.|.|.|:..|.|
  Rat   250 RAQDLWRQKKREEMEE--------ENRKI-LEFAKIQEQREGERMA-----RVQESEEKRVQRQN 300

  Fly   296 LLLDLLEAEYTAKSD-ERYRQQMQQEQMS-----------RQRTRQELDRYRQEVKHR------- 341
            ||:..||.....:.| ||.||::..|:.:           .||.|::.|| :|:.|.:
  Rat   301 LLIQKLEETLRQRDDLERVRQELYLEEYAEFIKLKMKEEVEQRLRKQRDR-KQDFKDQMALREVL 364

  Fly   342 ----KMAEMQMKRAEMATRQEEAPDTIN-QNSEKQLDEYRRRRAHGASLLAMIEDNHRKRAEATA 401
                |..|...|:|.:|...|:  |.|. .|::||   ..::..|..::..:||:...:......
  Rat   365 LQAAKEEEEAFKKAMLAKFAED--DRIELMNAQKQ---RMKQLEHKRAVEKLIEERRNQFLADKQ 424

  Fly   402 ENVQYFDMKAKIDAEQEERIKQERLAMLSQVPSSVLRYLPKHVLKSTD 449
            ..::...::.:......|.|::|||.:|.:..|.:|.||||.|.|..|
  Rat   425 RELEELQLQQRRQGCINEIIEEERLRLLKEHASKLLGYLPKGVFKKED 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7352	NP_649795.1	TPH	94..431	CDD:464007	95/366 (26%)
Mns1	NP_001007753.1	Interaction with BBOF1. /evidence=ECO:0000250|UniProtKB:Q61884	1..314		76/272 (28%)
		TPH	114..454	CDD:464007	95/366 (26%)