DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq2 and Coq2

DIOPT Version :9

Sequence 1:	NP_649789.1	Gene:	Coq2 / 40988	FlyBaseID:	FBgn0037574	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001037720.1	Gene:	Coq2 / 498332	RGDID:	1306722	Length:	374	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	192/299 - (64%)
Similarity:	228/299 - (76%)	Gaps:	9/299 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 PLQELVSAAKPYAQLMRIDRPIGTYLLFWPCAWSIALSADAGCWPDLTMLGLFGTGALIMRGAGC 133
            |||       ||.:|||:|:||||:||:.||.|||.|:||.||:||..||.||||||::||||||
  Rat    70 PLQ-------PYLRLMRLDKPIGTWLLYLPCTWSIGLAADPGCFPDWYMLSLFGTGAILMRGAGC 127

  Fly   134 TINDLWDKDIDAKVERTRLRPLASGQISQFDAIVFLSAQLSLGLLVLVQLNWQSILLGASSLGLV 198
            ||||:||:|.|.|||||..||:|:|.||.|.:.|||.|||:|.|.||:.||:.||.:||:||.||
  Rat   128 TINDMWDRDFDKKVERTANRPIAAGDISAFQSFVFLGAQLTLALGVLLHLNYYSIAMGAASLLLV 192

  Fly   199 ITYPLMKRVTYWPQLVLGMAFNWGALLGWCATQGSVNLAACLPLYLSGVCWTIVYDTIYAHQDKL 263
            :|||||||||:||||.||:.|||||||||.|.:||.:.|.|||||.|||.||::||||||||||.
  Rat   193 VTYPLMKRVTFWPQLALGLTFNWGALLGWSAVKGSCDPAVCLPLYFSGVMWTLIYDTIYAHQDKK 257

  Fly   264 DDLQIGVKSTALRFGENTKVWLSGFTAAMLTGLSAAGWACDQTVPYYAAVGVVGAHLVQQIYSLN 328
            ||..||:|||||.|.||||.|||||..||:..||..|.:..||:||||||..|||||..|||:::
  Rat   258 DDALIGLKSTALLFRENTKQWLSGFGVAMVGALSLVGASSGQTLPYYAAVAAVGAHLAHQIYTVD 322

  Fly   329 IDNPSDCAKKFISNHQVGLILFLGIVLGTLLKS--DESK 365
            |....||.:||.||..|||:||||||||.|.|.  ||:|
  Rat   323 IHRAEDCWEKFTSNRTVGLLLFLGIVLGNLYKDKPDETK 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq2	NP_649789.1	PT_UbiA	73..358	CDD:294241	184/284 (65%)
Coq2	NP_001037720.1	PT_UbiA	68..353	CDD:294241	181/282 (64%)
Coq2	NP_001037720.1	Allylic polyprenyl diphosphate-binding site. /evidence=ECO:0000255\|HAMAP-Rule:MF_03189	122..144		17/21 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352974
Domainoid	1	1.000	334	1.000	Domainoid score	I1089
eggNOG	1	0.900	-	-		E1_COG0382
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69192
Inparanoid	1	1.050	391	1.000	Inparanoid score	I1929
OMA	1	1.010	-	-		QHG57870
OrthoDB	1	1.010	-	-		D1343847at2759
OrthoFinder	1	1.000	-	-		FOG0004404
OrthoInspector	1	1.000	-	-		oto95639
orthoMCL	1	0.900	-	-		OOG6_101249
Panther	1	1.100	-	-	LDO	PTHR11048
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3123
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770