Protein Alignment ato and BHLHE22

DIOPT Version :10

• Sequence 1: NP_731223.1
• Gene: ato / 40975
• FlyBaseID: FBgn0010433
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_689627.1
• Gene: BHLHE22 / 27319
• HGNCID: 11963
• Length: 381
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 59/237 - (24%)
• Similarity: 83/237 - (35%)
• Gaps: 91/237 - (38%)

  Fly   132 VMGSSNVG---TCKTIPASA------GPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLYTEEF 187
            ::||:.||   :..::||.|      |....|.                :.||||..
Human   104 LVGSAGVGGDPSLSSLPAGAALCLKYGESASRG----------------SVAESSGG-------- 144

  Fly   188 QNFDFDNSALFDDSVEDDED----LMLFSGGEDFDGNDGS----FDLADG--------------- 229
                       :.|.:||.|    |:|.:|..|...:.|:    ...|:|
Human   145 -----------EQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPG 198

  Fly   230 -----------ENQDAAAGGSGKKRRGKQITPVVKRKR-------RLAANARERRRMQNLNQAFD 276
                       .......||||....|...:.....|:       ||..||||||||.:||.|.|
Human   199 GLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALD 263

  Fly   277 RLRQYLPCLGND--RQLSKHETLQMAQTYI----SALGDLLR 312
            .||..:|...:.  |:|||..||.:|:.||    .||.::.|
Human   264 ELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRR 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	bHLH_TS_amos_like	250..311	CDD:381558	29/73 (40%)
BHLHE22	NP_689627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..94
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..154		8/53 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..242		6/53 (11%)
		bHLH_TS_bHLHe22_bHLHb5	243..312	CDD:381524	29/63 (46%)