DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ato and TCF24

DIOPT Version :9

Sequence 1:NP_731223.1 Gene:ato / 40975 FlyBaseID:FBgn0010433 Length:312 Species:Drosophila melanogaster
Sequence 2:NP_001180431.1 Gene:TCF24 / 100129654 HGNCID:32275 Length:167 Species:Homo sapiens


Alignment Length:84 Identity:33/84 - (39%)
Similarity:41/84 - (48%) Gaps:9/84 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 DLADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAAN-ARERRRMQNLNQAFDRLRQYLPCLGND 288
            |...|......||..|..|.|.        .|..||| ||||.|:|.|..||..|::.||.:..|
Human    26 DSRPGRTGPGPAGPGGGSRSGS--------GRPAAANAARERSRVQTLRHAFLELQRTLPSVPPD 82

  Fly   289 RQLSKHETLQMAQTYISAL 307
            .:|||.:.|.:|.|||:.|
Human    83 TKLSKLDVLLLATTYIAHL 101

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
atoNP_731223.1 HLH 253..312 CDD:238036 26/56 (46%)
TCF24NP_001180431.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..60 14/41 (34%)
HLH 56..107 CDD:197674 22/46 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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