Protein Alignment Ada2b and Tada2a

DIOPT Version :10

• Sequence 1: NP_001027151.1
• Gene: Ada2b / 40966
• FlyBaseID: FBgn0037555
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_766150.1
• Gene: Tada2a / 217031
• MGIID: 2144471
• Length: 443
• Species: Mus musculus
• Alignment Length: 529
• Identity: 133/529 - (25%)
• Similarity: 207/529 - (39%)
• Gaps: 153/529 - (28%)

  Fly    13 CTNCQDDIQGIRVHCAEC--ENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVFRGKGAWT 75
            |..|...:....:.||||  ..|.||||||..|.|...||::|:|:.|.:...:|.     .:||
Mouse    17 CRGCSSYLTEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLD-----PSWT 76

  Fly    76 AREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNGTIGRAT-WTPAQSQRPRLID 139
            |:||:.||:|:...|||||:|::..:.||:.|:.::.|:..|:|..:..:| ....|::..:..|
Mouse    77 AQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEAAKAAD 141

  Fly   140 -----HTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNISLSSE 199
                 |:.||...|...:.||        .|.|   ||||.|..|..|:|..||..:.:|....:
Mouse   142 TAIPFHSADDPPRPAFDSLLS--------RDMA---GYMPARADFIEEFDNYAEWDLRDIDFVED 195

  Fly   200 DTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVS-NFFR--NRNYAQQQGLTKEQREFRDRF 261
            |:::...||:|.||||..||:||.|||:::||:.||: ..||  .|.|      .||.::..:..
Mouse   196 DSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLVNLRKFRLMERRY------PKEVQDLYETM 254

  Fly   262 RVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGPYG 326
            |.:|:.....|:::.:.|...|.|||.....|..||..|:|.......:
Mouse   255 RRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSARTY---------------- 303

  Fly   327 HGKTDHTHTSNGSHRPPSSSLHSPQPNLRKVEMSSGGEASSNSIAPRNTLHIADPTCSGALLPSK 391
                ||...:....|            |::..:|
Mouse   304 ----DHLKKTREEER------------LKRTMLS------------------------------- 321

  Fly   392 NYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPTNSAKGSQQHLQPLQQHPQL 456
            ..|...:.|||...    .:.....:|||.:                               |.:
Mouse   322 EVLQYIQDSSACQQ----WLRRQADIDSGLS-------------------------------PSV 351

  Fly   457 LQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLPQPPGSELLSHNELDLCKKHNITPTTY 521
            |.:.|          .|....|.::|   |.|         ||:|.|:..|.:||:...:.|..|
Mouse   352 LMASN----------SGRRSAPPLNL---TGL---------PGTEKLNEKEKELCQVVRLVPGAY 394

  Fly   522 LSVKTVCLS 530
            |..|:..|:
Mouse   395 LEYKSALLN 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	103/338 (30%)
Tada2a	NP_766150.1	COG5114	11..440	CDD:227445	133/529 (25%)