Protein Alignment Ada2b and Ada2a

DIOPT Version :10

• Sequence 1: NP_001027151.1
• Gene: Ada2b / 40966
• FlyBaseID: FBgn0037555
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_312792.6
• Gene: Ada2a / 1273779
• VectorBaseID: AGAMI1_013417
• Length: 512
• Species: Anopheles gambiae
• Alignment Length: 576
• Identity: 288/576 - (50%)
• Similarity: 358/576 - (62%)
• Gaps: 93/576 - (16%)

  Fly     1 MTTIADLFTKYNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSIL 65
            |:|  :||.||.|||||:||.||||||..|.:|:|||.|||||||||.|:|:|||||||:|  ||
Mosquito     1 MST--ELFAKYTCTNCQEDISGIRVHCVVCTDFELCLACFAAGAEIGPHRNDHSYQFMDSG--IL 61

  Fly    66 SVFRGKGAWTAREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNGTIGRATWTPA 130
            |:||||..|:||||:.||||||||||||||||||||||::.|:||||||:||:||||||.||..|
Mosquito    62 SIFRGKSGWSAREELHLLDAIEQYGFGNWEDISKHIETRTPEEAKEEYVSKFLNGTIGRHTWQTA 126

  Fly   131 QSQRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNIS 195
            ..|||.|.||| .||.|||....:..|||::..::||..||||||||.||||||||||||:|.:|
Mosquito   127 VDQRPILTDHT-SDDTGPLSQLLIQKLPPMDCTAEEAAALGYMPNRDDFEREYDPTAEQLVSTLS 190

  Fly   196 LSSEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFFR-NRNYAQQQGLTKEQREFRD 259
            |..:|.:||::||||.||||||||||||||||:||||||:.|||| |...|:|   |::|||||:
Mosquito   191 LQPDDEDVDMLLKLAQVDIYTRRLRERARRKRVVRDYQLIGNFFRGNMKRARQ---TRDQREFRE 252

  Fly   260 RFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGP 324
            |.|.|:||||..|:|||:.|||||:.||||.|||.|||:||:.::.||.|||||.|.|.:|:|||
Mosquito   253 RLRTYSQFYTSLEFERLISSLERERALRIRLSELNRYRWNGIQRVDECVHFEQHVAAAQYRNTGP 317

  Fly   325 YGHGKTDH------------THTSNGSHRPPSSSLHSPQ-----PNLRKVEMSSGGEASSNSIAP 372
            ||||:||:            ..:::||...|.... .||     .:.|:.|.:.|    |||...
Mosquito   318 YGHGRTDNRSRGGSGENVKGASSASGSGTGPMVGA-GPQTATHGASARRSEDARG----SNSTDR 377

  Fly   373 RNTLHIADPTCSGALLPSKNYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPT 437
            :.|.|..|..||.....|||.|||.:..:             ||...|            .:.||
Mosquito   378 KPTHHTDDRGCSDDSYSSKNCLDSLQREA-------------VTNPGG------------HHQPT 417

  Fly   438 NSAKGSQQHLQPLQQHPQLLQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLP-QPPGSE 501
            :..|....|                |..|..||||    |.|::..           | |.||.:
Mosquito   418 SGQKHHHHH----------------HHHQANAAGG----VGSLAAD-----------PAQQPGGQ 451

  Fly   502 LLSHNELDLCKKHNITPTTYLSVKTVCLSGAPSL----GSPMETSLRKFFIKCGWL 553
            ||:.||:.||...|:..|.||::|||.|| .|:|    .|..|:.::|:.:..|||
Mosquito   452 LLTSNEIQLCSTLNMPVTRYLTLKTVLLS-RPALDHNINSVAESIVKKYLVSRGWL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	222/343 (65%)
Ada2a	XP_312792.6	None