Protein Alignment CG9667 and ISY1

DIOPT Version :10

• Sequence 1: NP_649768.2
• Gene: CG9667 / 40960
• FlyBaseID: FBgn0037550
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001186398.1
• Gene: ISY1 / 57461
• HGNCID: 29201
• Length: 307
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 166/297 - (55%)
• Similarity: 208/297 - (70%)
• Gaps: 30/297 - (10%)

  Fly     1 MARNAEKAMTTLARWRAAKEVESGEKERRPYLASECHDLPRCEKFRLEIIRDISKKVAQIQNAGL 65
            ||||||||||.|||:|.|:..|...|||||:|||||.:||:.||:|.:||.:|||||||||||||
Human     1 MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGL 65

  Fly    66 GEFRIRDLNDEINKLLREKRHWENQISSLGGPHYRRYGPKMFDAEGREVPGNRGYKYFGAAKDLP 130
            |||||||||||||||||||.|||.:|..||||.|.:.||||.|.||:||||||||||||||||||
Human    66 GEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLP 130

  Fly   131 GVRELFEQDPP----------------------PPPRKSRAELMKDIDAEYYGYRDDEDGVLIPL 173
            |||||||::..                      |||||:||||||.||.|||||.|::|||::||
Human   131 GVRELFEKERQVRWLMPVIPALWEAEAGGSQALPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPL 195

  Fly   174 EERIERAAIQKAVQEWR----EKMARDGRIIDDEEEDEIYPLSGPAREAIEDAKARAAVEDPHGL 234
            |:..|:....:.|::|:    .::||..:..::|||:||...:....|:.|:.......:|..
Human   196 EQEYEKKLRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVTEEESDEEGSQEKGGDDSQ-- 258

  Fly   235 LASKFTAHVPVPTQQDVQEALLRQRKRELLEKYAGGT 271
              .||.||||||:||:::|||:|::|.|||:|||..|
Human   259 --QKFIAHVPVPSQQEIEEALVRRKKMELLQKYASET 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9667	NP_649768.2	Isy1	1..266	CDD:461860	162/290 (56%)
ISY1	NP_001186398.1	Isy1	1..288	CDD:461860	162/290 (56%)