DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7910 and SPBPB8B6.03

DIOPT Version :9

Sequence 1:	NP_001287222.1	Gene:	CG7910 / 40956	FlyBaseID:	FBgn0037547	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001018764.1	Gene:	SPBPB8B6.03 / 3361182	PomBaseID:	SPBPB8B6.03	Length:	547	Species:	Schizosaccharomyces pombe

Alignment Length:	541	Identity:	126/541 - (23%)
Similarity:	228/541 - (42%)	Gaps:	93/541 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LDFVLPRQKPKFSGIRNPLLKKSVVELVTQLRRGEITSVELVSAYIARVQEVNPSLNAVVEDRFE 87
            |:.:||.::       |.:...|::||.|.:.:|..||..:..|:..|....:..||..:|..|:
pombe    46 LNLILPPEE-------NAITNLSMLELATNIAKGNYTSYNVTKAFCHRAALAHQILNCCIEIFFD 103

  Fly    88 AALQDAKLADQFIEKASSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSLARKNMKAPQDG 152
            .||:.||..|...:|.|....        |..|:|.::|:...|.|...::|.::.......:..
pombe   104 EALKKAKELDDVFQKTSKVVG--------PFHGIPISLKDQVDLPGKDSSIGYVSLVGKPKTEIA 160

  Fly   153 DVVELVRAAGGIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEASLNGCGATTFG 217
            .:.::::..|.|..:.:..|...|:.:|.:|:.|...|..::..:|.||||||.:|.|.||:..|
pombe   161 LLAKILQDKGAIFYVKTTVPMAMMAPQTVSNLHGYTYNALNINLSSGGSSGGEGALLGSGASCCG 225

  Fly   218 VGSDISGSIRLPALFCGVFGHKPTGGLTSVKGHFPYSLTDKKFS--EMLQ--IGPITRFARDLPL 278
            :|:||.||||:|:.|.|::..||:.|..|      |......:|  |::.  |||:.|..:|:..
pombe   226 IGTDIGGSIRIPSCFQGLYALKPSTGRIS------YLNVTNSYSGQELIPSVIGPMARSLKDIEF 284

  Fly   279 LLEIMAGDKKHKLKMS-EPVA------LKDMKVYYAFGYSGFNCLTHPVVDFDIKLAITKAVTCL 336
            ..|.:...:..|:... .|:.      ||..|:.:....:......||    .|..|:.:.|..|
pombe   285 FTETVIASEAWKIDSKLLPIPWKNQSHLKSKKLIFGVLKTDGIVKPHP----PIIRALNEVVAVL 345

  Fly   337 ERGGVQSKKLDLKFLRNSLE-IALVSLVDLKGLPSIVTQRADRDPSMRLLMVELFNSIIGHSIFT 400
            |:.|.:..::.:.|.::.|: :..|...|.:...:..:|:.. :|     :|.:....:...||.
pombe   346 EKSGYEVIEISIPFQKDMLDTVVKVFSADARFEINNESQKTG-EP-----VVSVVKRFVSDKIFK 404

  Fly   401 KEAMVLEVMKRFNGLMATGNMEEYRVEAQKIKSHLNQLLGTQG-----VLIMPTFHTSALCFHTS 460
            |...|       |.....|| :.|::....::...|..:.|..     .:|.|.:.:      ||
pombe   405 KPITV-------NEWWDLGN-QVYKIRQMFLELWNNTAIQTLSGNSIDAIIAPIWAS------TS 455

  Fly   461 LLNVTGIDNLL--LFNILGLP-----------------ATHVPMGTNQR------------GMPI 494
            .|..:..|:|.  ||||...|                 .::.|:....:            .||:
pombe   456 FLPESKADHLYTSLFNICDCPCVVFPFTKVDANIDLSDVSYKPLNEEDKENNDMYDPVLFDNMPV 520

  Fly   495 GLQVVAAQYQDKLCLKVAAEL 515
            .||||..:.:::.||..|:.:
pombe   521 CLQVVTKKLEEEKCLAAASSI 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	122/523 (23%)
CG7910	NP_001287222.1	PRK07488	41..525	CDD:236030	122/523 (23%)
SPBPB8B6.03	NP_001018764.1	Amidase	79..535	CDD:302749	112/493 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1324
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I1345
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9291
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	7	6.890