DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7910 and SPCC550.07

DIOPT Version :9

Sequence 1:	NP_001287222.1	Gene:	CG7910 / 40956	FlyBaseID:	FBgn0037547	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_588099.1	Gene:	SPCC550.07 / 2539478	PomBaseID:	SPCC550.07	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	566	Identity:	147/566 - (25%)
Similarity:	223/566 - (39%)	Gaps:	139/566 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DFVLPRQK-PKFSGIRNP----LLKK-SVVELVTQLRRGEITSVELVSAYIARVQEVNPSLNAVV 82
            |.||...| |...|:..|    |.:| ....|...::..::||||||:|:..|.......:|.|.
pombe    32 DTVLNVTKIPSECGLLTPKEIELTEKYDATALAEMIKDRKVTSVELVTAFCKRAAIAQQLVNCVN 96

  Fly    83 EDRFEAALQDAKLADQFIEKASSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSLARKNMK 147
            |..:|.||..|...|::..|..|...        |:.|||.:|||...:|..:.....||:.|:.
pombe    97 ELFYEEALARAAELDEYYAKTGSLVG--------PLHGVPVSVKEHISIKNHTATASFLAKANII 153

  Fly   148 APQDGDVVELVRAAGGIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEASLNGCG 212
            |.:|.|:|..||.||.:....:..|:..|..|||:|:.|..:||::.:.|..||||||.:|.|..
pombe   154 AEKDSDLVATVRKAGAVFYCRTPQPQAIMHLETSSNLTGVTVNPFNRKLTPGGSSGGEGALLGIK 218

  Fly   213 ATTFGVGSDISGSIRLPALFCGVFGHKPTGGLTSVKGHFPYSLTDKKFSEMLQIGPITRFARDLP 277
            |:..|:||||.||||.||...|:||.:|:....|.||  .......:.:.:..:||:.|..||:.
pombe   219 ASVLGIGSDIGGSIRSPAANNGLFGLRPSTLRLSRKG--CQGAVSGQETILGVVGPLGRSVRDMN 281

  Fly   278 LLLEIMAG-----DKKHKLKM-----SEPVALKDMKVYYAFGYSGFNCLTHPVVDFDIKLAITKA 332
            |.::....     |....|.|     :.|   |.:||......:..|  ..|.|...:::||.:.
pombe   282 LFMKACIDSQPWLDDASLLPMPWRSVAPP---KTLKVGIMRSDNVVN--PQPPVARAMQMAIDQL 341

  Fly   333 VTCLERGGVQSKKLDLKFLRNSLEIALVSLVDLKGLPSIVTQRADRDPSMRLL-----------M 386
                      ||..|.            .|||::.|        |...|..|:           .
pombe   342 ----------SKNPDF------------DLVDVEPL--------DHKYSWDLISEMYWLDGGKVY 376

  Fly   387 VELFNSI----------IGHSIFTKEAMVLEVMKRFNGLMATGNMEEYRVEAQKIKSHL-----N 436
            .:|||.:          |.|....|...:..|.|      .|...:|||   .:...||     :
pombe   377 YDLFNKVGEPILPLTEWIMHQPNVKPHDITAVWK------LTAARDEYR---NRYLKHLQAYGVD 432

  Fly   437 QLLGTQGVLIMPTFHTSALCFHTSLLNVTGIDNLLLFNILGLPA-----------------THVP 484
            .||...|....|....:....:||           ::|:|.|||                 :::|
pombe   433 VLLTPVGPSPAPKLGEAKYWTYTS-----------VWNLLDLPAVVFPVTTVDPKLDVKDESYIP 486

  Fly   485 MGTNQRG------------MPIGLQVVAAQYQDKLCLKVAAELEAV 518
            |......            .|:.||:|..::||:   ::.|.|:.:
pombe   487 MNEQDAANYETYSPEDYLDAPVSLQLVGKRWQDE---ELLAALDKI 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	140/544 (26%)
CG7910	NP_001287222.1	PRK07488	41..525	CDD:236030	140/544 (26%)
SPCC550.07	NP_588099.1	Amidase	76..523	CDD:279733	132/514 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1324
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I1345
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9291
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	7	6.890