Protein Alignment CG2767 and AKR1E2

DIOPT Version :10

• Sequence 1: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: XP_011518017.2
• Gene: AKR1E2 / 83592
• HGNCID: 23437
• Length: 324
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 124/326 - (38%)
• Similarity: 185/326 - (56%)
• Gaps: 40/326 - (12%)

  Fly    24 QASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVKREELFIVTKVPPVSNRP 88
            |||..::..|:..|::|||||.|.|..|.||:.:|..::..:..|.|:||:|||.||:....::.
Human    17 QASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 81

  Fly    89 HEVEPTIKKSLEDLQLDYVDLYLVHTP------------------FTININEDGSFKLDKEGLME 135
            ..||...:|||:.|:|:|:||||:|.|                  |.::........|| |..|.
Human    82 SLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLD-ESNMV 145

  Fly   136 VDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEHHVYLQQRDL 198
            :...|:....|.|||.||..||.|:||||||:.:|:.|||.  ..:.:|..||||.|.||.|::|
Human   146 IPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 210

  Fly   199 VDFCKSENITVTAYSPLGS--KGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWI 261
            :.||:|.:::||||.|||.  :|:              ||:|.|.:|.||..|||:|||:|:|:.
Human   211 ISFCQSRDVSVTAYRPLGGSCEGV--------------DLIDNPVIKRIAKEHGKSPAQILIRFQ 261

  Fly   262 IDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFKNQ 326
            |...|..||.|..|:.:|:|:.|||||||..::..:.||::|:|:   |.|...:.|.::.|..:
Human   262 IQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRL---AMFPITKNHKDYPFHIE 323

  Fly   327 Y 327
            |
Human   324 Y 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2767	NP_649757.1	AKR_AKR1I_CgAKR1	4..309	CDD:381381	119/306 (39%)
AKR1E2	XP_011518017.2	AKR_SF	17..324	CDD:444925	123/324 (38%)