Protein Alignment CG10445 and EDA16

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_176309.2
• Gene: EDA16 / 842407
• AraportID: AT1G61140
• Length: 1280
• Species: Arabidopsis thaliana
• Alignment Length: 1132
• Identity: 287/1132 - (25%)
• Similarity: 433/1132 - (38%)
• Gaps: 364/1132 - (32%)

  Fly     7 SDTTEIHKQSCSIQDQ------------------SSVP----VPDS---SGEINNW--------- 37
            ||....:..|||.||.                  ||||    |.|.   |||.|.|
plant   314 SDLDRPNNYSCSFQDNKTVHVKVKPEAESEKVVYSSVPGEFSVRDDAYLSGETNRWWSGASSSAV 378

  Fly    38 ------------MEPEPV----DSLELSG----------EYADNESAIFVSASEYNEKKAQIDQL 76
                        |.|:..    ||.::|.          :|...:.:.....:||  |..||.|.
plant   379 SYQTDIEKGYSYMAPQTALPSQDSGKISSNHFYDSDTCLQYVVEDPSPVTQNNEY--KDFQIQQG 441

  Fly    77 VQKILTMEQQQRQLEENASETKELCDLKLHLEKLNARLEAL-GEFLDTLRLREDQQEIKIED--N 138
            .::.:    |.|.::...|               ||..|:: ....:.:...:|..::.|.:  .
plant   442 DREYI----QPRGIDSQFS---------------NASFESVQSHSSECISDSDDDSDVCIIEPYG 487

  Fly   139 SELVDH----TEQPKWSNLYSGLNRYRQKANHTAAQFYQHKSNII--DSLKTLYEP----IQPRP 193
            ...:.|    .:.|..|:.||.::....::.....|  .:|.|:|  .:|:.|.:|    |.|
plant   488 QSAIPHRPLAMKMPVVSSEYSTVSHNFNQSGGLKLQ--SNKENMIFQAALQDLTQPNSEAILP-- 548

  Fly   194 AIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQ--KISGGILADDMGLGKTLSMIALILASEETK 256
                    ..:|.|.||:||:..|.||..:|..  ..||||||||.|||||:|.|||||
plant   549 --------DGVLTVPLLRHQRIALSWMAQKETSGFPCSGGILADDQGLGKTVSTIALIL------ 599

  Fly   257 NRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEP--PEKRTCHVKTKKINQ 319
               :|..|.|..           |:|..|..:||.|.|:|    :..|  |..|:.|     ...
plant   600 ---KERSKPAQA-----------CEESTKKEIFDLESETG----ECAPLKPSGRSKH-----FEH 641

  Fly   320 FRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQW 384
            .::|.:::...||.          :.|.                .|| |:|.||||||.|||.||
plant   642 SQLLSNENKVGGDS----------VGKV----------------TGR-PAAGTLVVCPTSVMRQW 679

  Fly   385 AHEVASKVAQNA-IRVLTFHGPNR----HEIGIEAFRSYDLVITSYNLVVNEL------------ 432
            |.|:..||...| :.||.:||.:|    ||:.     .||:|:|::::|..|:
plant   680 ADELHKKVTSEANLSVLVYHGSSRTKDPHELA-----KYDVVVTTFSIVSMEVPKQPLVDDEDEE 739

  Fly   433 --------------------------KRYGN--------TSPLFAVYWNRVILDEAHIIRNSKTN 463
                                      |:.|:        :.||..|.|.||:||||..|:|.||.
plant   740 KDGVHDGGTAATGFCSNKKRKYPPDSKKKGSKKKKVEFLSGPLAKVSWFRVVLDEAQSIKNYKTQ 804

  Fly   464 CCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESML-----GHRRL 523
            ...:...|||...|.|:|||:||...|:::..||:....:.....:...:...:.     |:::|
plant   805 VARACWGLRAKRRWCLSGTPIQNSIDDLYSYFRFLKYDPYSSYVLFCSTIKNPITRNPVKGYQKL 869

  Fly   524 NFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREK 588
            ..|:|.:||||||..|.....:.:||...|||..|..:..|...|..|.|.|:   |||....|.
plant   870 QAILKTVMLRRTKGSLLDGKPIISLPPKSIELRKVDFTVEERDFYSKLEAESR---TQFREYAEA 931

  Fly   589 GNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPG 653
            |....||                                        :.||::||||||.|.||.
plant   932 GTVKQNY----------------------------------------VNILLMLLRLRQACDHPL 956

  Fly   654 LM-----------IGMLRGALTA--------------EDVQ------------------------ 669
            |:           :|:.:..:.:              ||..
plant   957 LVNGEYSFTWESSVGLAKKQIQSDASLAICGICNDAPEDAVASVCGHVFCKQCIYERLTGDSNHC 1021

  Fly   670 -----NVKVDASDVEGQLKM-DVLAELDKFDETDSEDDCCDEEDSTRRDGNFK--LEVIKDEIKE 726
                 ||::..|.:..:.:: |.:.::.:...::|...|.| ||........|  ||:::
plant  1022 PFANCNVRLTISSLSSKTRLDDAMPDMQERATSNSLSPCSD-EDLPYGSSKIKAALEILQ----- 1080

  Fly   727 ENVPWDSGDDLPTASSFED--QLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDK 789
                     .||.|....|  |:...|....|:        |.|.....|.:|...::   ..:|
plant  1081 ---------SLPKAHDLTDSNQISENREYSGLS--------ITPVKNEGMSVDVPIKV---AGEK 1125

  Fly   790 IIVTSQWVSYLAIVRKRL--QDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVG 852
            .||.|||...|.::...|  ..:.:..||  |.::...|:..::|||...|..|:::||.|..:|
plant  1126 AIVFSQWTKMLNLLEASLVSSHIQYRRLD--GTMSVAARDKAVQDFNTLPEVTVMIMSLKAASLG 1188

  Fly   853 LNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCK-LEIAK 916
            ||:..|.|:|::||.|||..|.||.||.:|.|||:|..:.|:..:||||.||.:||..| :.:|.
plant  1189 LNMVAACHVLMLDLWWNPTTEDQAIDRAHRIGQTRPVTVVRFTVKDTVEDRILALQQKKRMMVAS 1253

  Fly   917 VVLPEEGGEVTKCVGGGLNLAELKKLF 943
            ....:|.|...    ..|.:.:|..||
plant  1254 AFGEDEKGSRQ----SHLTVEDLSYLF 1276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	246/940 (26%)
		DEAD-like_helicase_N	209..534	CDD:475120	114/384 (30%)
EDA16	NP_176309.2	HepA	<547..1256	CDD:440319	230/850 (27%)
		RING-HC_CHR27-like	984..1035	CDD:438504	5/50 (10%)