DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10445 and AT1G11100

DIOPT Version :9

Sequence 1:	NP_001246974.1	Gene:	CG10445 / 40938	FlyBaseID:	FBgn0037531	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	NP_001320184.1	Gene:	AT1G11100 / 837651	AraportID:	AT1G11100	Length:	1270	Species:	Arabidopsis thaliana

Alignment Length:	1095	Identity:	278/1095 - (25%)
Similarity:	411/1095 - (37%)	Gaps:	358/1095 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TEIHKQSCSIQDQSSVPVPDSSGE-----------INNWMEPEPVDSLELSGEYADNESAIFVSA 63
            |::.|:...|..|::.|..|..|.           ..|..:|:|        |.:..||
plant   371 TDVGKEYPFIPPQTAFPGQDIDGRSFYSCFDSDDCFQNVTDPDP--------ETSRTES------ 421

  Fly    64 SEYNEKKAQIDQLVQKILTMEQQQRQLEENASETKELCDLKLHLEKLNARLEALGEFLDTLRL-- 126
                     :|.||.            :|:....|..|      ..|::......|.|.:.|:
plant   422 ---------LDYLVG------------DEDHEYIKRTC------FNLSSFSSGTVESLSSKRIPE 459

  Fly   127 REDQQEI-KIEDNSELVD-H----TEQPKWSNLYS----------GLNRYRQKAN---HTAAQ-F 171
            |||..|| |||...|.|: |    .::|.:|:.:|          ||.....|.|   |...| .
plant   460 REDDSEIHKIESYGEFVNPHQYLPVQRPVFSSEHSTGSQTLNNCGGLKFESNKGNMNFHADLQDL 524

  Fly   172 YQHKSNIIDSLKTLYEPIQPRPAIDDLEKQP--ALLLVRLLKHQQSCLKWMQFRER--QKISGGI 232
            .||.|                      |..|  .:|.|.||:||:..|.||..:|.  ....|||
plant   525 SQHSS----------------------EASPPDGVLAVSLLRHQRIALSWMSQKETSGNPCFGGI 567

  Fly   233 LADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGK 297
            ||||.|||||:|.|||||....|.....||                            |.:..|
plant   568 LADDQGLGKTVSTIALILTERSTPYLPCEE----------------------------DSKNGG- 603

  Fly   298 EEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQK---DLLAKTPEPEVFSSDEEE 359
                        |                 |.:....||.:|.|   |.|.|
plant   604 ------------C-----------------NQSDHSQVVFNENKVVEDSLCK------------- 626

  Fly   360 EHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNA-IRVLTFHGPNR----HEIGIEAFRSYD 419
               ..|| |:|.||:|||.|:|.|||.|:..||...| :.||.:||.:|    ||:.     .||
plant   627 ---MRGR-PAAGTLIVCPTSLMRQWADELRKKVTLEAHLSVLVYHGCSRTKDPHELA-----KYD 682

  Fly   420 LVITSYNLVVNELKR----------------------YGN------------------------- 437
            :|||:|:||..|:.:                      :|:
plant   683 VVITTYSLVSVEVPKQPRDRADEEKGGIHDGGVESVGFGSNKKDLPNSQKKGTKKRKHMDCEPVE 747

  Fly   438 --TSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNV 500
              :.||..|.|.||:||||..|:|.||....:...|.|...|.|:|||:||...|:::..||:..
plant   748 FLSGPLAQVSWFRVVLDEAQSIKNYKTQASIACSGLHAKRRWCLSGTPIQNSIADLYSYFRFLKY 812

  Fly   501 PNFQDLQQWKKNLNESML-----GHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQL 560
            ..:...|.:.:.:...:.     |::.|..|:|.:||||||..|.....:.:||...|||..|..
plant   813 DPYSSYQTFCETIKNPISSYPGEGYKTLQAILKKVMLRRTKDTLLDGKPVISLPPKSIELRRVDF 877

  Fly   561 SKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSL 625
            :|.|...|..|...|:..|.::   .|.|....||
plant   878 TKEERDFYSKLECDSRDQFKEY---AEAGTVKQNY------------------------------ 909

  Fly   626 GYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVD-----ASDVEGQLKMD 685
                      :.||::||||||.|.|| |::..|..:.:||.|:.:..:     ...:|..|.:.
plant   910 ----------VNILLMLLRLRQACGHP-LLVSSLSWSSSAEMVKKLPYEKLTFLLHRLEASLAIC 963

  Fly   686 VLAELDKFDETDSE------DDCCDEEDSTRRDGN----------------FKLEVIKD---EIK 725
            .:..:...|...|.      :.|..|  ...||.|                |..|.:::   ::.
plant   964 GICNVAPKDAVVSLCGHVFCNQCICE--CLTRDNNQCPLSYCKVGLEISSLFSRETLENAMLDLH 1026

  Fly   726 EENVPWD--------SG---DDLPTASS-FEDQLDSARALKLLNPQNPIF--------------- 763
            :.:.|.|        ||   ::||..|| .:..||..::|.  .||:|..
plant  1027 KLDAPCDRTTSDPVGSGEPCENLPCGSSKIKAALDILQSLS--RPQSPATVMNDVNQSSENGENN 1089

  Fly   764 -----QFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTA 823
                 .|..|:...|..:..:..:   ..:|.||.:||...|.::...|:....:...|:|::|.
plant  1090 QQLDKSFSLPATPAKSSVGGVVNV---AGEKAIVFTQWTKMLDLLEAGLKSSGIQYRRFDGKMTV 1151

  Fly   824 KEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKP 888
            ..|:..::|||...:..|:::||.|..:|||:..|.|::::||.|||..|.||.||.:|.|||:|
plant  1152 PARDAAVQDFNTLPDVSVMIMSLKAASLGLNMVAACHVIMLDLWWNPTTEDQAIDRAHRIGQTRP 1216

  Fly   889 TFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKLF 943
            ..:.|:..:||||.||.:||..|   .|:|....|..........|::.:|..||
plant  1217 VKVVRFTVKDTVEDRILALQQKK---RKMVASAFGEHENGSRESHLSVEDLNYLF 1268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_001246974.1	HepA	<90..945	CDD:223627	262/1004 (26%)
CG10445	NP_001246974.1	DEAD-like_helicase_N	209..534	CDD:421690	108/388 (28%)
AT1G11100	NP_001320184.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	94	1.000	Domainoid score	I2515
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132523at2759
OrthoFinder	1	1.000	-	-		FOG0000507
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101296
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820