Protein Alignment CG10445 and hltf

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_693071.2
• Gene: hltf / 564651
• ZFINID: ZDB-GENE-030131-3306
• Length: 942
• Species: Danio rerio
• Alignment Length: 833
• Identity: 207/833 - (24%)
• Similarity: 350/833 - (42%)
• Gaps: 210/833 - (25%)

  Fly   180 DSLKTLYEPIQPRPAIDDL------EKQPA-LLLVRLLKHQQSCLKWMQFRER------------ 225
            :.||..::.:     .|||      |.:|| .:...||.||:..|.||..||.
Zfish   195 EELKNAFDKL-----FDDLMEDKTKEMEPAEAVCTPLLSHQKQALSWMSSRENSNDLPPFWEENK 254

  Fly   226 ----------------QKISGGILADDMGLGKTLSMIALILAS-----------------EETKN 257
                            :|:.||||||||||||||:.||||:::                 ...|.
Zfish   255 GLYFNVLTNFAVKKRPEKVLGGILADDMGLGKTLTTIALIVSNFHNGKPLPLEKCKGPSMPSAKR 319

  Fly   258 RKREEKKKALTLKWTQE------FNRVYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKK 316
            ::...|:|.:..:.:||      ..|::...:|         |:|        |:|:|...|.|.
Zfish   320 KQATSKEKGVDSEESQESMGLSPLKRLHDDTVR---------ENG--------PQKKTKTTKKKS 367

  Fly   317 INQFR--ILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMS 379
            .|..:  :|.||...|   |.:|.....::   |..:..........:|.|....| ||:|||:|
Zfish   368 ANTKKAVVLLDDVEFA---AALECSSSQVV---PSKKCVKKSSVPSEISAGSVARA-TLIVCPLS 425

  Fly   380 VMCQWAHEVASKVAQN-AIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKRYGN--TSPL 441
            |:..|..:....:..: .::|..::|..|:. .:......|:|:|:||::.::   :||  :|||
Zfish   426 VLSNWLDQFEQHIRTDVTVKVYLYYGSERNR-SVSLLSEQDVVLTTYNVLSSD---FGNKASSPL 486

  Fly   442 FAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDL 506
            ..|.|.||:|||.|::||.......:|.:|::...|.|:|||:||...|:|.||.|:.:..| |:
Zfish   487 HNVKWLRVVLDEGHVVRNPNALQSKAVLELQSERRWILSGTPIQNSLKDLFMLLSFLKLKPF-DV 550

  Fly   507 QQWKKNLNE------SMLGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEM 565
            ::|...:.:      ..:|.:.|..::|.:.|||||........:..||..::.:..|.||..|.
Zfish   551 KEWWSRIIQRPVTMGDRVGLKNLQALVKGITLRRTKNSKVGGRTLVQLPERRVFVQYVTLSGMER 615

  Fly   566 AVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPG 630
            ..|:.:....|.|..::.   ::|....||..
Zfish   616 EKYERVKGEGKNIVGRYF---QEGTFMANYAD--------------------------------- 644

  Fly   631 EKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDE 695
                   :|.:|:||||.||||.|:     |..||.||..       ...:|:..::.::.....
Zfish   645 -------VLTILMRLRQCCCHPSLV-----GNYTAADVPG-------TPSELRERLIQKITLVLN 690

  Fly   696 TDSEDDCCDEEDSTRR----------------------DGNFKLEVIKDEIKEENVPWDSGDDLP 738
            :.|:::|....||.|:                      ....|..:.:.:||.:.:....|:...
Zfish   691 SGSDEECAICLDSLRQPVITYCAHVFCRPCICEVIRSEKEQAKCPLCRAQIKTKELVEYPGEQAE 755

  Fly   739 TAS-SFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTND----KIIVTSQWVS 798
            |.| :.|:...|::||.|::                       .||...|:    |.:|.||:..
Zfish   756 TRSDTGENWRSSSKALALMS-----------------------NLLKLRNEDPTVKSMVVSQFTG 797

  Fly   799 YLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDF--NANNEKRVLLLSLTAGGVGLNLNVANHM 861
            :|.::...|::..:.....:|.|..:.|...:.||  :......::||||.||||||||..|:.:
Zfish   798 FLDVLEVALREYGFSFTRLDGSLIQRARAKAIEDFQDSTPGSPTIMLLSLKAGGVGLNLTAASQV 862

  Fly   862 LIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEI 914
            .::|..|||..|.|..||.:|.||::...|.:::.:|:||:.:..:|..|.|:
Zfish   863 FVMDPAWNPAAEDQCVDRCHRLGQSRDVVITKFIVKDSVEENMVKIQKKKQEL 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	207/833 (25%)
		DEAD-like_helicase_N	209..534	CDD:475120	105/386 (27%)
hltf	XP_693071.2	HIRAN	54..147	CDD:400928
		HepA	<226..921	CDD:440319	199/797 (25%)
		DEXHc_HLTF1_SMARC3	226..584	CDD:350829	105/386 (27%)
		RING-HC_HLTF	692..746	CDD:438172	8/53 (15%)