Protein Alignment CG10445 and rrp1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_594246.1
• Gene: rrp1 / 2542440
• PomBaseID: SPAC17A2.12
• Length: 897
• Species: Schizosaccharomyces pombe
• Alignment Length: 857
• Identity: 219/857 - (25%)
• Similarity: 354/857 - (41%)
• Gaps: 252/857 - (29%)

  Fly   172 YQHKSNIIDSLKTLYEPIQ---PRP--AID----DLEKQPALLLVRLLKHQQSCLKWMQFRERQK 227
            |:.|.......|.|::.:|   |.|  .||    :.:.|.|.|||.||.||.....||:..|:..
pombe   204 YERKVQPEHVTKELHQLLQHNTPSPFDTIDLQLKNEQVQSAGLLVSLLPHQVEGHAWMESMEQSS 268

  Fly   228 ISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDE 292
            ..||::|||||||||:..|||:|                     ||
pombe   269 KCGGVMADDMGLGKTIQTIALLL---------------------TQ------------------- 293

  Fly   293 EESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDE 357
                                                          :.:|.|.||
pombe   294 ----------------------------------------------KSQDPLRKT---------- 302

  Fly   358 EEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKV-AQNAIRVLTFHGPNRHEIGIEAFRSYDLV 421
                          .|:|..::::.|||.|:::|| ....:.|...||..:..:.......||:|
pombe   303 --------------NLIVVSVALLHQWAEELSTKVHPSKKLSVYIHHGSTKKNLDSYELSQYDVV 353

  Fly   422 ITSYNLVVNELKR---YGNTSP----------LFAVYWNRVILDEAHIIRNSKT---NCCNSVCQ 470
            :|:|:::..|:|:   :.|.:|          |....|.|::|||||.|||..|   .||   .:
pombe   354 LTTYSMLAYEMKQNDAFNNNNPATATPPPACSLLETSWYRIVLDEAHTIRNRDTLAAKCC---VK 415

  Fly   471 LRAHCHWALTGTPVQNRGVDVFALLRFVNVPNF-----------QDLQQWKKNLNESMLGHRRLN 524
            |.|...|.|:|||:||...:.::||:|:.:..:           :.|:.::.::.|:.|  :||.
pombe   416 LDAKYRWCLSGTPIQNHIDEFYSLLKFLRIKPYCVWSLFAKDISRPLKSYRADIVEAAL--KRLR 478

  Fly   525 FIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVY--QILSAISKKIFTQFLLQRE 587
            .::...:.||||:....:..:..||...|..:.|.|...|.|:|  |:.||       |.|:...
pombe   479 ILLASTVFRRTKETRVNNLPIVNLPPKTIRTVSVNLLPEERALYNEQMSSA-------QSLVDNY 536

  Fly   588 KGNS-DLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCH 651
            ..|. ||:.|.                                       ::||.||||||||||
pombe   537 FNNDHDLSRYG---------------------------------------FLLVSLLRLRQFCCH 562

  Fly   652 PGLM-IGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDC------------- 702
            |.|: ...|..:....|.:||:.....:: .|.::.:|.|..|:.:...|.|
pombe   563 PWLVKSSSLDNSFRIRDSENVRNACKSLD-PLTIERIATLQDFNCSVCLDPCLAPVFIIPCGHFT 626

  Fly   703 CDEEDST---RRDGNFKLEVI--KDEIKEENVPWDSGDDLPTASSFEDQLDSARALKL------- 755
            |.|..|.   ::.|:.....|  |..:...|:..||..|.....:....|:|.:.|:|
pombe   627 CQECMSMLVGQKYGSSSTSTIIAKCPMCRGNIVQDSLVDATILQAIHGPLNSLKQLELDMNQSFS 691

  Fly   756 ------LNPQNPIFQFI-----------RPSAKLKMVIDKLEELL-TGTNDKIIVTSQWVSYLAI 802
                  |..:|.|.|..           :.|:||......:.::: :..|:||:|.||:..||.:
pombe   692 EQESIKLRWENRIDQMFTKKFGKRASEWKSSSKLNQARQTILDIIGSKRNEKILVYSQFSQYLCL 756

  Fly   803 VRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLH 867
            |...|:..:...:.::|.::|.:|:..|..||.:.:..|:|:||.||.|||||.:|||:::.:..
pombe   757 VSHMLKLENIRHVRYDGTMSANQRQKSLHSFNNDKDVLVMLVSLKAGSVGLNLTIANHVILQEPF 821

  Fly   868 WNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVL-PEEGGEVTKCVG 931
            :||.:|.||.||::|.||.||..:||::.:||:|:||.|:|..|.::.|..| ..|...:::
pombe   822 YNPSIEDQAIDRVHRLGQQKPVTVYRFITKDTIEERIVSVQRKKRQLVKEALDSNENNPLSR--- 883

  Fly   932 GGLNLAELKKLF 943
              |:..||..||
pombe   884 --LDKEELLYLF 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	212/830 (26%)
		DEAD-like_helicase_N	209..534	CDD:475120	79/352 (22%)
rrp1	NP_594246.1	HepA	<244..874	CDD:440319	202/791 (26%)
		RING_Ubox	603..663	CDD:473075	11/59 (19%)