Protein Alignment CG10445 and rrp2

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_596602.1
• Gene: rrp2 / 2540464
• PomBaseID: SPBC23E6.02
• Length: 1040
• Species: Schizosaccharomyces pombe
• Alignment Length: 1073
• Identity: 257/1073 - (23%)
• Similarity: 415/1073 - (38%)
• Gaps: 355/1073 - (33%)

  Fly     3 SSSPSDTTEIHKQSCSIQDQS-------------------------SVPVPDSSGEINNWMEPEP 42
            |.|.||...:..:| |:.|..                         |:||..::|       |..
pombe   190 SDSESDDNNVRTKS-SLNDHDKVNMKEKRNLELAFMNSKRKKLELPSLPVLSTAG-------PSY 246

  Fly    43 VDSLELSGEYADNESAIFVSASEYNEKKAQIDQLVQ-------KILTMEQQQRQL----EENASE 96
            .:||.|...:..|...:|.:.....:     |:.:|       .|...:::..::    :...|:
pombe   247 TNSLALPPFHHHNNYKMFNTTHTLED-----DKFLQGKGTSNNPISLSDEEDNEINFQNKRYGSD 306

  Fly    97 TKELCDLKLHLEKLNARLEALGEFLDTLRLREDQ----QEIKIED-NSELVDHTEQPKWSNLYSG 156
            :..|....||    :::|...|:.|..|:...|:    :...:.| |::.|...:|.:...|:
pombe   307 SVILPGGLLH----DSKLPEPGKHLFHLQWYHDRFHNIEGFNLSDSNNQKVQDDQQQQLEELF-- 365

  Fly   157 LNRYRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQ 221
                                      |.|.|.:...|.|  .|..||.|:..|::||:..|.|::
pombe   366 --------------------------KDLDEQLVNDPTI--REGTPAGLIPTLMEHQKEGLMWLK 402

  Fly   222 FRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKI 286
            ..|.....|||||||||||||:..:||::.
pombe   403 RLEESSKKGGILADDMGLGKTVQALALLVT----------------------------------- 432

  Fly   287 SMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPE 351
                            .|||.::  |||
pombe   433 ----------------RPPESKS--VKT------------------------------------- 442

  Fly   352 VFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVA-QNAIRVLTFHGPN-RHEIGIEA 414
                                ||::.|:|::.||.:|:.:|:| .:...|...||.: :|:|. |.
pombe   443 --------------------TLIITPVSLLQQWHNEILTKIAPSHRPTVYIHHGSSKKHKIA-EQ 486

  Fly   415 FRSYDLVITSYNLVVNELKR---YGNT------------SPLFAVYWNRVILDEAHIIRNSKTNC 464
            ..|||:|:|:||::..|.|.   |..:            .|.|...|.|||||||..|:|..|..
pombe   487 LMSYDIVLTTYNVIAYEFKNKMAYDKSIEDNAPIKKFEHLPFFEAEWYRVILDEAQTIKNRNTLA 551

  Fly   465 CNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKK--------NLNESMLGHR 521
            ....|.|.:...|.|:|||:||...:.::|::|:.:..:.|...:.|        |:|.| ...:
pombe   552 ARGCCLLESTYRWCLSGTPMQNGVEEFYSLIKFLRIKPYSDWSSFSKDFTIPLSSNINTS-APMK 615

  Fly   522 RLNFIIKPLMLRRTKQ-KLQASG--DMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFL 583
            |...::|.::|||||. |:....  .:|...::|.|   ..||.:||..|..|.:.::....::|
pombe   616 RFRGLLKAVLLRRTKNTKIDGKPILTLPPKTAVKSE---TDLSSSEMEFYNTLQSGAQIQMRKYL 677

  Fly   584 LQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQF 648
               ::|....:|.||                                        |||||||||.
pombe   678 ---QEGTITTHYGSL----------------------------------------LVLLLRLRQA 699

  Fly   649 CCHPGLMIG----------------MLRGALTAEDVQNVKVDASDVEGQLKMDVLAEL------- 690
            ||||.|::.                .:...:..|.|..:|: ...::..|.|||:|||
pombe   700 CCHPWLIVAREAAVDDNDSFQAKNRAIYNQIYPEAVNRLKL-IETLQCSLCMDVVAELLIIVPCG 763

  Fly   691 ----------------DKFDETDSED-----DCCDEEDSTRR----------DGNFKLEVIKDEI 724
                            |...:|.:|:     ..|:|...|.|          .|...:....:::
pombe   764 HFLCRECLTHVITSSEDMAKQTSNENISPKCSVCEEYIDTERLLSYALFRRYSGMAPIVDADNKL 828

  Fly   725 KEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRP-----SAKLKMVIDKLEELL- 783
            :.||:    .:.||  ..:.:.|:        |.|..:..|..|     |.|::..::.::|::
pombe   829 RTENI----SELLP--KQYSNILE--------NRQMGMKIFTDPKHWTTSTKIEKALNAVKEIIK 879

  Fly   784 TGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTA 848
            ....|||::.||:||:|.:.....:....:.|.:.|.|:..||...|.:|..:...||||:||.|
pombe   880 KQPTDKILIFSQFVSFLELFTVPFRQEGIKYLMYTGGLSTAERNQALINFEVDPNVRVLLISLKA 944

  Fly   849 GGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLE 913
            |.|||||..|||::|:|..|||.:|.||.||.:|.||.||..|.|.:..:|:|:|:.:|||.|.|
pombe   945 GNVGLNLTCANHVIILDPFWNPYIEEQAVDRAHRIGQDKPVNILRIVTNNTIEERVLALQDRKRE 1009

  Fly   914 IAKVVLPEEG-GEVTKCVGGGLNLAELKKLFEM 945
            :....|.|:| .|:::     ||..||..||.|
pombe  1010 LIDSALGEKGLREISR-----LNTKELSFLFGM 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	222/898 (25%)
		DEAD-like_helicase_N	209..534	CDD:475120	84/349 (24%)
rrp2	NP_596602.1	HepA	<380..1016	CDD:440319	207/808 (26%)
		RING_Ubox	742..812	CDD:473075	14/69 (20%)