Protein Alignment CG10445 and csb-1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_510607.2
• Gene: csb-1 / 181674
• WormBaseID: WBGene00000803
• Length: 957
• Species: Caenorhabditis elegans
• Alignment Length: 1008
• Identity: 195/1008 - (19%)
• Similarity: 345/1008 - (34%)
• Gaps: 390/1008 - (38%)

  Fly     2 ESSSPSDTTEIHKQSCSIQDQSSVPVPD----------------SSGEINNWMEPEPVDSLELSG 50
            |..:|...|   .::.|:.|...|.:.|                ||.:.:...|||..:.
 Worm     6 EPENPDSGT---PKTLSVDDDDIVVIEDQNTPKYREAALRRSNSSSSDFDEKWEPELDEE----- 62

  Fly    51 EYADNESAIFV----SASEYNEKKAQIDQLV--------QKILTMEQQQRQLEENASETKELCDL 103
            ::.:|::.:..    |.|....:::...:.|        ::...:|:.:::..::.|.::...|
 Worm    63 DFCENDADVLAEPISSKSRKKSRRSDSSEFVPSEESDDDEEYEVLEKSRKKGRKSGSSSRSSSD- 126

  Fly   104 KLHLEKLNARLEALGEFLDTLRLREDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTA 168
                           :|:::    :|.::.|   ::.|:|..:.   .|..:.:::.:.:|.
 Worm   127 ---------------DFIES----DDNEDYK---SAGLLDDNDS---KNFKARIDKLKPEAT--- 163

  Fly   169 AQFYQHKSNIIDSLKTLYEPI--QPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQKISGG 231
                   |.::|:.....|..  ..:|     .|..|.:..:|.|.||..::|:| ::....|||
 Worm   164 -------SELVDTRMVTSEEYGKSSKP-----WKVNAGVWNKLHKFQQEGVEWLQ-KKTDHRSGG 215

  Fly   232 ILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESG 296
            ||||:||||||:..:..:.:.:||
 Worm   216 ILADEMGLGKTIQSVVFLRSIQET----------------------------------------- 239

  Fly   297 KEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEH 361
                      .|| |.||..::
 Worm   240 ----------ART-HYKTTGLD------------------------------------------- 250

  Fly   362 LSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFH---GPNRHEIGIEAFRSYD---- 419
                     ..|:||.:|::.||..|:.....:..:.:|..|   |.....:| ..||...
 Worm   251 ---------TALIVCHVSIIAQWIKELNQWFPKARVFLLHSHCSTGRQEDYVG-SIFRKLQRRRK 305

  Fly   420 ------LVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWA 478
                  :::|:|:| ..:||:     |:....|..|||||.|.|||..|.|..::.:|.....:.
 Worm   306 EYPDGAIILTTYSL-FTKLKK-----PIVKHLWQVVILDEGHYIRNENTKCSIAMRKLMTTQRFI 364

  Fly   479 LTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESMLGHRRLN-----------------FI 526
            |||||.|||..:.:.|:.||:.....|...:.:|....:.....||                 ..
 Worm   365 LTGTPFQNRLSEFWKLVDFVHPGRLSDSATFHRNFTHIINAGANLNCSPEAAAKAYECLVALHIA 429

  Fly   527 IKPLMLRRT----KQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQRE 587
            :|||:|||.    |:.||       ||..:..::..:|||.:..:|.                 |
 Worm   430 VKPLILRRLQEDHKEVLQ-------LPEKQEIVLSCELSKRQRRLYM-----------------E 470

  Fly   588 KGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKS-LGYNPGEKILGIYILVLLLRLRQFCCH 651
            .|||                    .:.|||.||.||: :|.|               .|...|.|
 Worm   471 YGNS--------------------HQVNEIIERRLKAFVGIN---------------HLTNICNH 500

  Fly   652 PGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFK 716
            ||:
 Worm   501 PGI-------------------------------------------------------------- 503

  Fly   717 LEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEE 781
                                                .:.|:|.:|.|..|:.|.|::|.....::
 Worm   504 ------------------------------------YRSLSPASPKFGSIKDSGKVEMTFKLFDD 532

  Fly   782 LLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSL 846
            ......:::|:.:|..:.:.::...|.:...:.:...|..:|..|..:::.|..:...:|.|::.
 Worm   533 WFKSPTNRVILFTQRRTVITMMEYFLAEKGIKCVSLTGADSAAARPKIIKKFEDDVSIKVFLMTT 597

  Fly   847 TAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVE--QRIKSLQD 909
            .|||:||||..||.::|.|..||||.:.||::||||.|||....|||.:...|:|  :..|.:|
 Worm   598 RAGGLGLNLTCANKVIIFDPDWNPQADNQAKNRIYRMGQTNDVAIYRLVSNGTIEDLKFFKQVQ- 661

  Fly   910 CKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKL 942
             |..:|..:|  ...|:.:.|... .||:|.:|
 Worm   662 -KENLAARLL--HNAEIDQFVPNN-TLADLFRL 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	169/844 (20%)
		DEAD-like_helicase_N	209..534	CDD:475120	77/354 (22%)
csb-1	NP_510607.2	HepA	<193..670	CDD:440319	156/747 (21%)