DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Taf7 and taf7

DIOPT Version :9

Sequence 1:	NP_649748.1	Gene:	Taf7 / 40934	FlyBaseID:	FBgn0024909	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_775367.1	Gene:	taf7 / 100002261	ZFINID:	ZDB-GENE-020419-18	Length:	362	Species:	Danio rerio

Alignment Length:	449	Identity:	145/449 - (32%)
Similarity:	222/449 - (49%)	Gaps:	105/449 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KVKQAEHKARDDGV-ELESQFIMRVPKELADTVHEAINAGT--IKDRLTIQLDPDLRYGEVRIDD 101
            ||.:...|:::|.. |||||||:|:|:|.|.||.....:.:  :||||||:|..|.|:|.||:|.
Zfish     6 KVGKVGTKSKEDAPHELESQFILRLPQEYASTVRRIAQSSSMNMKDRLTIELHADGRHGIVRVDR 70

  Fly   102 QILYTKLVDLPTVVESYKTIDNKSFYKSADICQILICKEERE-----DETEKESPNKNKKKDPNK 161
            ..|..||||||.::||.||:|.|:|||:|||||:|:|..:.:     :|....:.:|:||||.:|
Zfish    71 VPLACKLVDLPCILESLKTVDKKTFYKTADICQMLVCTLDGDLYPPLEEPTGTTDSKSKKKDKDK 135

  Fly   162 VDKKYLFPHGITPPCKNVRKRRFRKTLKKKNVEAPEIEKEVKHLLRIDNEAVRVDYEIINEEDKP 226
             |||:::.||||.|.||.||||||||.|||.:|:|::|||||.||..|.|||.|.:|:|.|::.
Zfish   136 -DKKFVWNHGITLPLKNTRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSVRWEVIAEDES- 198

  Fly   227 MDELEQSDIKPYNDADDDLQDESTMHASEKTIMEMSSQRHLQVESDDDEASNFPSHRAPNMGVAV 291
                        .:.|:.| ..|.:.:|..|                   |....|.:......:
Zfish   199 ------------KEPDNSL-SLSNLESSPGT-------------------SGHKGHGSSVQHDEL 231

  Fly   292 HDIFGEEVSSTDDEDEPDRGNNTMQRRVMEESSRLSADDSRMSDFFGASGSNTGAGVVKMEQNVF 356
            .:||.:..||::|||              ||..|...:|..:.|        |...:|:......
Zfish   232 REIFNDISSSSEDED--------------EEGDRHDDEDLNIMD--------TEDDMVRQLHEKL 274

  Fly   357 SKSMFGHEASSPKLSAAGSSSNLAAPSGFYDSQMLAKREEFENMEFIDEPQPQYTQQQVQQKINQ 421
            ::|..|.:.:.                  .:||::        ||:             |.:||.
Zfish   275 NESDGGRDEND------------------RNSQIV--------MEY-------------QMQINN 300

  Fly   422 LTRQIRELKAQQVQKSTEIASIQNATLKQRMQETLDNLYTQVIERELE-LKDFENMLES 479
            |..:::|.:|::.|:...|..::|..|:.|.|..|:.:..|. |:|:| |...:..|:|
Zfish   301 LKAKLQETRARKKQQEKLIMEVENQALRDRFQGLLNGMIRQE-EQEMEQLASLQEQLDS 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf7	NP_649748.1	TAFII55_N	55..213	CDD:282507	87/164 (53%)
taf7	NP_775367.1	Taf7	15..349	CDD:227701	139/429 (32%)
taf7	NP_775367.1	TAFII55_N	22..186	CDD:282507	87/164 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574255
Domainoid	1	1.000	166	1.000	Domainoid score	I3837
eggNOG	1	0.900	-	-		E1_COG5414
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3974
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1348389at2759
OrthoFinder	1	1.000	-	-		FOG0001971
OrthoInspector	1	1.000	-	-		oto39079
orthoMCL	1	0.900	-	-		OOG6_102177
Panther	1	1.100	-	-	LDO	PTHR12228
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1474
SonicParanoid	1	1.000	-	-		X1289
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790