Protein Alignment alphaTub84D and TUB4

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_013313.1
• Gene: TUB4 / 850909
• SGDID: S000004202
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 463
• Identity: 139/463 - (30%)
• Similarity: 221/463 - (47%)
• Gaps: 48/463 - (10%)

  Fly     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDG--QMPSDKTVGGGDDSFNTFFSETGAGKHVPRA 65
            |.|::..||.|..:|...|.....||.|..||  |:|...|  ..||....||.|....|..|||
Yeast     4 EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSST--ERDDDTKPFFRENSRNKFTPRA 66

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADQ 128
            :.:|.||:|:.:|. .|:|..|.|.......:  .|.|::|.| |.||....|.:|::|.|..|.
Yeast    67 IMMDSEPSVIADVE-NTFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILNKIDKEIDS 129

  Fly   129 CTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHT 193
            ....:||.:.||..||||||..|.|:|.|...|.||....::|:|| :.|..||:.||:||....
Yeast   130 TDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPA-RSSEVVVQSYNTILALRR 193

  Fly   194 TLEHSDCAFMVDNEAIYDICRR-----NLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLT 253
            .:|.||...:.||.::.:|..:     |:|::     :.|:||..|:||:|.|:||...:...::
Yeast   194 LIEDSDATVVFDNASLLNISGKVFRNPNIDLQ-----HTNQLISTIISSVTNSIRFPSYMYSSMS 253

  Fly   254 EFQTNLVPYPRIHFPLVTYAPVIS---AEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMAC 315
            ...:.|:|.|.:||...::.|..|   .:...|:..|..::.....:|:|.:|.....:..|...
Yeast   254 SIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNV 318

  Fly   316 CMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTV--------VPGGDLAKVQ 372
            .....|:|.|:.::.|:.  |.::.|:|..|..:...|.|..:.|.:        |.|
Yeast   319 YNTIIGNVEPRQISRAMT--KLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSG------- 374

  Fly   373 RAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWY-VGEGME-----EGEFSEAREDLAALEKD 431
               .||||.:.:...:....:.||.::||.||::.| ||:..:     :.||:|:||.:.:|.:|
Yeast   375 ---MMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMED 436

  Fly   432 YEEVGMDS 439
            |.....||
Yeast   437 YVAAEQDS 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	137/461 (30%)
TUB4	NP_013313.1	gamma_tubulin	3..437	CDD:276957	135/454 (30%)