Protein Alignment alphaTub84D and TUBG1

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001061.2
• Gene: TUBG1 / 7283
• HGNCID: 12417
• Length: 451
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 139/445 - (31%)
• Similarity: 242/445 - (54%)
• Gaps: 26/445 - (5%)

  Fly     2 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAV 66
            ||.|::.:||.|.|||...|:..|.||||.|:|.:....|  .|.|..:.||.:.....::||||
Human     3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHYIPRAV 65

  Fly    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADQC 129
            .:||||.|:..:....|.:|::||.:...:.  .|.||:|.| ::.|::|.:.:.|.|.:.||..
Human    66 LLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDREADGS 129

  Fly   130 TGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYP-APQVSTAVVEPYNSILTTHT 193
            ..|:||::.||..||||||..|.|:|||:..|.||....::|:| ..::|..||:||||:||...
Human   130 DSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKR 194

  Fly   194 TLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTN 258
            ..:::||..::||.|:..|....|.|:.|:::.:|:|:..|:|:.|.:||:.|.:|.||.....:
Human   195 LTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIAS 259

  Fly   259 LVPYPRIHFPLVTYAPVISAEK-AYHEQLSVAEITNACFEPANQMVKVDPRHGK-------YMAC 315
            |:|.||:||.:..|.|:.:.:. |...:.:|.::.....:|.|.||..    |:       |:|.
Human   260 LIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVST----GRDRQTNHCYIAI 320

  Fly   316 CMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSN 380
            ..:.:|:|.|..|:.::..|:.::...|:.|.|...:|.::.:.|.:.....::.:     |::|
Human   321 LNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGL-----MMAN 380

  Fly   381 TTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDLAALEKDY 432
            .|:|:..:.|...::|.:..:.||:..:..|.|.:..|.|   :||.:..|..:|
Human   381 HTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEY 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	139/445 (31%)
TUBG1	NP_001061.2	gamma_tubulin	3..435	CDD:276957	138/443 (31%)