Protein Alignment alphaTub84D and TUBA4A

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_047301630.1
• Gene: TUBA4A / 7277
• HGNCID: 12407
• Length: 457
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 419/447 - (93%)
• Similarity: 434/447 - (97%)
• Gaps: 0/447 - (0%)

  Fly     2 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAV 66
            |||||:||||||||:|||||||||||||||||||||||||:|||||||.|||.||||||||||||
Human    11 RECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAV 75

  Fly    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTG 131
            ||||||||:||:|.|.||||||||||||||||||||||||||||||||:|.||||||||:|||||
Human    76 FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTG 140

  Fly   132 LQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLE 196
            |||||:||||||||||||||||||||||||||||||||::|||||||||||||||||||||||||
Human   141 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 205

  Fly   197 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP 261
            |||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||
Human   206 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVP 270

  Fly   262 YPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRGDVVPK 326
            ||||||||.||||||||||||||||||||||||||||||||||.|||||||||||:|||||||||
Human   271 YPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPK 335

  Fly   327 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391
            |||||||.|||||:|||||||||||||||||||||||||||||||||||||||||||||||||||
Human   336 DVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 400

  Fly   392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAE 448
            |||||||||||||||||||||||||||||||||:|||||||||||:||.:.|.||.|
Human   401 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSYEDEDEGEE 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	413/436 (95%)
TUBA4A	XP_047301630.1	PTZ00335	11..457	CDD:185562	418/445 (94%)