Protein Alignment alphaTub84D and Tubd1

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001185974.1
• Gene: Tubd1 / 56427
• MGIID: 1891826
• Length: 486
• Species: Mus musculus
• Alignment Length: 555
• Identity: 113/555 - (20%)
• Similarity: 198/555 - (35%)
• Gaps: 196/555 - (35%)

  Fly     5 ISIHVGQAGVQIG----------------------NACWELYCLEHGIQPDGQMPSDKTVGGGDD 47
            :::.:||.|.|||                      |..::..|.|.
Mouse     4 VTVQLGQCGNQIGFEVFDALFRDSHCSQGLCSKRDNEAYQASCRER------------------- 49

  Fly    48 SFNTFFSETGAGKHVPRAVFVDLEPTVVDE-----VRTGTYRQLFHPEQLITGKEDAANNYARGH 107
                ||.|...|..|.|||.||:||.|:::     .::|.:....|..  ...|:.:.||:|.|:
Mouse    50 ----FFREEENGVPVARAVLVDMEPKVINQTLSKAAQSGRWNYGQHTS--FCQKQGSGNNWAYGY 108

  Fly   108 YTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVY 172
            ...|.:..:.:::.|:...::|..|.||.|..|..||||||..:.:.::|...|....|:...::
Mouse   109 SVHGPKHEESIMNLIQTEVEKCDSLSGFFIIMSMAGGTGSGLGAFVTQKLQDQYSSSLKMNQIIW 173

  Fly   173 PAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSS 237
            |. .....:|:.||||||.......||...:.:|:|::.||.:.::|::.::.:||:::...:.|
Mouse   174 PY-GTGEVIVQNYNSILTLSHLYRSSDALLIHENDAVHKICAKRMNIKQISFRDLNQVLAHQLGS 237

  Fly   238 I-------TASLRFD------------------------GALNV-------DLTEFQTNLVPYP- 263
            :       .:|..:.                        .|.|:       ||.|   :|||:|
Mouse   238 VFQPTYSEDSSFHYRRNPLDSGTVGPQACLMPRIFVWSLSATNLSFYPQTGDLME---HLVPHPE 299

  Fly   264 -----------------------------------------------RIHFPLVTYAPV--ISAE 279
                                                           ::..||....|:  .||.
Mouse   300 FKMLGVRNIPQMSAASLAYSAFTWAGLLKHLRQMLISSAKMEEGINWQVRPPLTGLPPIGKASAH 364

  Fly   280 KAYHEQLSVA--------EITNACFEPANQMVKVDPRHGKYMACCMLYRGDVVPKDVNAAIATIK 336
            |.:|...|:|        |:.:|..|...     ||         .||...:.|.|   |.:..|
Mouse   365 KEHHFNTSLANLVVLRGREVHSADVEGFK-----DP---------ALYTSWLEPVD---AFSVWK 412

  Fly   337 TKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAK 401
            |:|...                           |.:::..::||:..:.:....:..|...|::.
Mouse   413 TQRAFD---------------------------KYEKSAALVSNSQLLVKPLDMIVGKAWNMFSS 450

  Fly   402 RAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG 436
            :||:|.|...||||.:|.::...|..:...|..:|
Mouse   451 KAFIHQYTKFGMEEEDFLDSFALLEQVVASYGSLG 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	113/555 (20%)
Tubd1	NP_001185974.1	delta_zeta_tubulin-like	2..483	CDD:276958	112/551 (20%)