Protein Alignment alphaTub84D and Tubb5

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_035785.1
• Gene: Tubb5 / 22154
• MGIID: 107812
• Length: 444
• Species: Mus musculus
• Alignment Length: 452
• Identity: 184/452 - (40%)
• Similarity: 271/452 - (59%)
• Gaps: 13/452 - (2%)

  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRA 65
            |||.:.|..||.|.|||...||:...||||.|.|....|..:  ..|..:.:::|...||:||||
Mouse     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDL--QLDRISVYYNEATGGKYVPRA 63

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCT 130
            :.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.|:.|.
Mouse    64 ILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCD 128

  Fly   131 GLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTL 195
            .||||.:.||.|||||||..:||:.::..:|..:....|:|.|:|:||..||||||:.|:.|..:
Mouse   129 CLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLV 193

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            |::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|:|
Mouse   194 ENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMV 258

  Fly   261 PYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRGDVVP 325
            |:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|...|||||:|:....::||.:..
Mouse   259 PFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSM 323

  Fly   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            |:|:..:..::.|.:..||:|.|...|..:...||        ..::.||..:.|:|||.|.:.|
Mouse   324 KEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIGNSTAIQELFKR 380

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAR---EDLAALEKDYEEVGMDSGDGEGEGAEE 449
            :..:|..|:.::||:|||.||||:|.||:||.   .||.:..:.|::...:..:..||.|||
Mouse   381 ISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEE 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	179/440 (41%)
Tubb5	NP_035785.1	PLN00220	1..429	CDD:215107	179/437 (41%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		6/20 (30%)