DRSC/TRiP Functional Genomics Resources

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Protein Alignment: alpha-Est10 and NLGN3

Sequence 1:NP_001246962.1 Gene:alpha-Est10 FlyBaseID:FBgn0015569 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_851820.1 Gene:NLGN3 HGNCID:14289 Length:848 Species:Homo sapiens

Alignment Length:633 Identity:167/634 (26%)
Similarity:239/634 (38%) Gaps:176/634 (28%)


  Fly    51 IKTKSGPVRGVK---RNTIWG--GSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTS-PAD 109
            :.|..|.:||.:   .:.|.|  ..|..   :|:|.||:|:.||..||....|....:.|. |..
Human    44 VNTHFGKLRGARVPLPSEILGPVDQYLG---VPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPV 105

  Fly   110 KPLQTH---------MFFRK---------YAGSEDCLYLNVYV---------------------- 134
            .|...|         ::|..         ...:||||||||||                      
Human   106 CPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICR 170

  Fly   135 ---------------------KDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVIV 177
                                 :|::....:||||:|:||.|.  |.:.:|.......| .:|:::
Human   171 KGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYM--EGTGNMIDGSILASYGNVIVI 233

  Fly   178 TVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHF 242
            |:.||:|.|||||..|..  ..||.||.|||.|||||.:||..||||...||:||...|.:....
Human   234 TLNYRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSL 296

  Fly   243 LALSPQTEGLIHKAIVMSGSVLCPWT---QPPRNNWAYRLAQKLGYTG-DNKDKAIFEFLRSMSG 303
            |.||..:|||..:||:.|||.|..|.   ||.:  :...||.|:|... |..|  :.:.||..|.
Human   297 LTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVK--YTSLLADKVGCNVLDTVD--MVDCLRQKSA 357

  Fly   304 GEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEG 368
            .|:|:       .|.:..|...|||||:     :..|:...|..||:........:|.|....||
Human   358 KELVE-------QDIQPARYHVAFGPVI-----DGDVIPDDPEILMEQGEFLNYDIMLGVNQGEG 410

  Fly   369 LLFY-----PEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAY--FGDEPCNQAN 426
            |.|.     ||........|.  :..|.:.:..|.   |:.::.....:|..|  :.|....:..
Human   411 LKFVEGVVDPEDGVSGTDFDY--SVSNFVDNLYGY---PEGKDTLRETIKFMYTDWADRDNPETR 470

  Fly   427 MMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMR----GVCH 487
            ....:.|.:..::..|....|....|..| |||.|.|.|.           |...|:    ...|
Human   471 RKTLVALFTDHQWVEPSVVTADLHARYGS-PTYFYAFYHH-----------CQSLMKPAWSDAAH 523

  Fly   488 GDDLCYIFHSMLSHQSAPDSPEHKVITGMVDV-------------------WTSFAAHGDPNCES 533
            ||::.|:|       ..|       :.|..|:                   ||:||..||||   
Human   524 GDEVPYVF-------GVP-------MVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN--- 571

  Fly   534 IKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNKL 581
                  .|:...|.| .....::||          |..|:.:...::|
Human   572 ------KPVPQDTKF-IHTKANRFE----------EVAWSKYNPRDQL 602

Known Domains:


GeneSequenceDomainRegion External IDIdentity
alpha-Est10NP_001246962.1 COesterase 49..542 CDD:278561 160/593 (27%)
Aes <132..>279 CDD:223730 64/194 (33%)
NLGN3NP_851820.1 COesterase 36..624 CDD:278561 167/634 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C92123128
eggNOG 1 0.900 E1_COG2272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D754103at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.840

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