Protein Alignment Ir84a and grik4

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 684
• Identity: 138/684 - (20%)
• Similarity: 252/684 - (36%)
• Gaps: 196/684 - (28%)

  Fly    97 RTAVLVLNS----EHVLVRRQVFGVASEAGYFNNSLAWFILGSGRESLPVEQLIDQLLS--GYRM 155
            :||.:::::    .||::.|     |||.|..:....:.:.......|.::.|.||.::  |:.:
Zfish   211 KTATIIVDANATMSHVILER-----ASELGMLSVYYTYILTSLEFSLLRLDDLADQRVNIVGFSV 270

  Fly   156 -----GIDADITVALR-------------GPDNASMLFYD--------VYRISRQAN---TPLII 191
                 ....|..::|.             |...:|.|.:|        |..::|..|   |.|..
Zfish   271 FNRTHPFFQDFVLSLNRSWQENCDHAPFAGTPLSSALLFDAVHTVVAAVQELNRSQNVGATQLSC 335

  Fly   192 EKKGLWTHSGGYQKFGNFKNTWVIRRRNFLN-VTLIGSTVLTEKPPGFGDMEYLADDKQ------ 249
            :...:|.|.....              |:|. |.|.|.|         |.:|:.:..::
Zfish   336 KSSKIWEHGTSLM--------------NYLRMVELEGLT---------GHIEFNSKGQRSNYALR 377

  Fly   250 --------LQQLD--------PMQRKTYQLFQLVERMFNLSLAIS-------------------- 278
                    |:|:.        .|:||...| .:.:.:||.:|.|:
Zfish   378 IMQNSRDGLRQIGQWHSEQGLSMERKLPSL-NVTDTLFNTTLTITTILENPYVMLRANHQELEGN 441

  Fly   279 ------LTDKWGELLD---------------------NGSWSGVMGQVTSREADFAVCPIRFVLD 316
                  ..|...||.|                     ||:|:|::|::.||:||.||..:....:
Zfish   442 DRYEGFCVDMLKELADILKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAE 506

  Fly   317 RQPYVQYSAVLHTQNIHFLFR-HPRRSHIKNIFFEPLSNQVW-WCVLALVTGSTILLLF------ 373
            |:..:.:|....|..|..::| |..|......|.:|.|..|| :.:||.:..|.:|.|.
Zfish   507 REKVIDFSKPFMTLGISIMYRVHIGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPY 571

  Fly   374 -----HVRLERMLSNMENRFSF---VWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSF 426
                 |..|:...|.:.|::|.   .||. :..::|||    |     |..|||.:..:...|:.
Zfish   572 EWYNPHPCLKGRCSLLINQYSLGNSFWFP-VGGFMQQGSTIAP-----RALSTRCVSGVWWAFTL 630

  Fly   427 MLMQFYGAFIVGSLLSESARSIVNLQALYD----SNLAIGMENISYNFPIFTNTSNQLVRDVYVK 487
            :::..|.|.:...|..:  |..|.::::.|    :.:..|..:.......|.|:..|..:.::..
Zfish   631 IIISSYTANLAAFLTVQ--RMEVPIESVDDLADQTAIEYGTMHGGSTMTFFQNSRYQTYQRMWNF 693

  Fly   488 KICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDE---AEFCDLQEV---MFNLP 546
            ...|.....:.|.::|..|::...:|:          |||..|:|   ...|:|.::   :....
Zfish   694 MYSKQPSVFVKSTEEGIARVLNSNYAY----------LLESTMNEYYRQRNCNLTQIGGLLDTKG 748

  Fly   547 YDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPD---CSLFKTSQAE-VDLEHFAP 607
            |..|  ||.||.:|:....|:|..:....|:...:||.    |   |...:..:|: :.:|:...
Zfish   749 YGIG--MPLGSVYRDEFDLAILRLQEENRLEILKRKWW----DGGKCPKEEDHRAKGLGMENIGG 807

  Fly   608 ALFALALAMVASALVFLLELFLHWLPDFRRRLGT 641
            ....|...::.:..:.:||..  |:  .|...||
Zfish   808 IFVVLVCGLLVAIFMAVLEFV--WM--LRHTPGT 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	4/18 (22%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	24/94 (26%)
		Lig_chan	353..602	CDD:459656	61/281 (22%)
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	37/217 (17%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	82/383 (21%)