Protein Alignment Ir84a and GluRIA

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 116/597 - (19%)
• Similarity: 215/597 - (36%)
• Gaps: 155/597 - (25%)

  Fly   125 NNSLAWFILGSGRESLPVEQ--LIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANT 187
            |.|..|.        .|.||  .|.::|.  ::.||. ::..:|..::...:.|.::.:....|:
  Fly   385 NTSKGWV--------TPWEQGEKISRVLR--KVEIDG-LSGEIRFDEDGRRINYTLHVVEMSVNS 438

  Fly   188 PLIIEKKGLW--------THSGGY--------QKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPP 236
            .|  ::...|        .||..|        ...|::.     |...::..:|:....|:.|..
  Fly   439 TL--QQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYD-----RNHTYIVSSLLEEPYLSLKQY 496

  Fly   237 GFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDN----GSWSGVMG 297
            .:|:        .|...|..:.....|..::.....:...|.|........:|    |.|.|::|
  Fly   497 TYGE--------SLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVG 553

  Fly   298 QVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNI-----FFEPLSNQVW 357
            ::..:|||.|:..:....:|:..:.:|....|..|..:.:.|    :|..     |..|||.::|
  Fly   554 ELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKP----VKQTPGVFSFLNPLSQEIW 614

  Fly   358 WCVLALVTGSTILLLFHVRLE-------------------------RMLSNME--------NRFS 389
            ..|:....|.:.:|.|..|..                         ..||..:        |.|:
  Fly   615 ISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFT 679

  Fly   390 FV---WFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSE---- 443
            .:   |:: |..::|||    |.:     .:.|:..::...|:.:|:..|.|.:...|..|
  Fly   680 MLNSFWYS-LAAFMQQGCDITPPS-----IAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVA 738

  Fly   444 --------SARSIVNL-QALYDS------NLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSG 493
                    :.::.||. ..||.|      ...||:.|..:.:    ..:||
  Fly   739 PIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEY----MNANQ-------------- 785

  Fly   494 EHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDE----AEFCDLQEVMFNLPYDS-GSVM 553
            .|::.:..:|..|:.|.:        ..|.||:|...:|    ...||..:|..|:.... |...
  Fly   786 HHSVHTYDEGIRRVRQSK--------GKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVAT 842

  Fly   554 PKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQA--EVDLEHFAPALFALALAM 616
            |.|||.|:.|..|:|..:..|.|.....||...:.:|:|.:.:..  |:.|.:.|...:.|...:
  Fly   843 PIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELSLSNVAGIYYILIGGL 907

  Fly   617 VASALVFLLELF 628
            :.:.:|.::|.|
  Fly   908 LLAVIVAIMEFF 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/81 (23%)
		Lig_chan	353..602	CDD:459656	63/314 (20%)
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..456	CDD:380603	15/83 (18%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	87/445 (20%)
		Lig_chan	610..906	CDD:459656	66/327 (20%)