Protein Alignment Ir84a and Ir25a

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 674
• Identity: 137/674 - (20%)
• Similarity: 238/674 - (35%)
• Gaps: 171/674 - (25%)

  Fly    73 NYRVQFYRPEMSANFEDLMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFI----- 132
            |..:.|.:|.....:.|.:  |..|| ...||.|..|         |.|.||:.:|..|:
  Fly   277 NATIMFMKPMAYTQYRDRL--GLLRT-TYNLNEEPQL---------SSAFYFDLALRSFLTIKEM 329

  Fly   133 LGSGRESLPVEQL-IDQLLSGY--RMGID-ADITVALRGPDNASMLFYDVYRISRQANTPLIIEK 193
            |.||.....:|.| .|....|.  :..:| .|....:..|.:     |..:.:..|:..|.
  Fly   330 LQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFTKITEPTS-----YGTFDLVTQSTQPF---- 385

  Fly   194 KGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQR 258
                 :...:.||....|...||..:.:|...||..:     .|......:.|::|::.|  ...
  Fly   386 -----NGHSFMKFEMDINVLQIRGGSSVNSKSIGKWI-----SGLNSELIVKDEEQMKNL--TAD 438

  Fly   259 KTYQLFQLVERMF-------------------NLSLAISLTD---------KWGELLDNGSWSGV 295
            ..|::|.:|:..|                   |...||...|         |:|.:.:||.|:|:
  Fly   439 TVYRIFTVVQAPFIMRDETAPKGYKGYCIDLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGI 503

  Fly   296 MGQVTSREADFAVCPIRFVLDRQPYVQYSAVLH-TQNIHFLFRHPRRSHIKNIFFEPLSNQVWWC 359
            :.::..::||..:..:..:.:|:..:.::...: ...|..:.:.|........|...|...||.|
  Fly   504 VKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLC 568

  Fly   360 VLALVTGSTILLLFHVR---------LERMLSNMENR-FSF---VWFTMLETYLQQG---PANEI 408
            :||....::.|:....|         .|:...:.|.| |:.   :||.|.....|.|   |.|
  Fly   569 ILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMTSLTPQGGGEAPKN-- 631

  Fly   409 FRLFSTRLLISLSCIFSFMLMQFY----GAFIVGSLLSESARSIVNLQALY-------------- 455
               .|.||:.:...:|.|:::..|    .||:..|.|.....|:.:|...|
  Fly   632 ---LSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKILYAPLNGSSAMT 693

  Fly   456 ----------------------DSNLAIGMENIS-YNFPIFTNTSNQLVRDVYVKKICKSGEHNI 497
                                  ||..|:....:: :::|         |.|.|.|......|..:
  Fly   694 YFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYP---------VSDKYTKMWQAMQEAKL 749

  Fly   498 -MSLQQGAERIIQGR----FAF-HTAIDRMYRLLLELQMDEAEFCDLQ---EVMFNLPYDSGSVM 553
             .:|.:...|:....    ||| ..|.|..|     ||:..   ||||   |.....||  ...:
  Fly   750 PATLDEAVARVRNSTAATGFAFLGDATDIRY-----LQLTN---CDLQVVGEEFSRKPY--AIAV 804

  Fly   554 PKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE-----VDLEHFAPALFALA 613
            .:||..::...:|:|.......|:...:||.  :.|.:|.|..:.|     :.:::.. .:|.:.
  Fly   805 QQGSHLKDQFNNAILTLLNKRQLEKLKEKWW--KNDEALAKCDKPEDQSDGISIQNIG-GVFIVI 866

  Fly   614 LAMVASALVFLLELFLHWLPDFRR 637
            ...:..|.:.|  :|.:|...:|:
  Fly   867 FVGIGMACITL--VFEYWWYRYRK 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	11/38 (29%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	13/73 (18%)
		Lig_chan	353..602	CDD:459656	68/319 (21%)
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	38/171 (22%)
		PBP2_iGluR_putative	438..836	CDD:270435	85/423 (20%)