Protein Alignment Ir84a and Grik1

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001104587.1
• Gene: Grik1 / 29559
• RGDID: 2732
• Length: 949
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 124/523 - (23%)
• Similarity: 206/523 - (39%)
• Gaps: 90/523 - (17%)

  Fly   152 GYRMGIDADITVALR--GPDNA----SMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFK 210
            |.|...|.|| ::|:  |.:.|    |...|.|::            |.|:|..:.|.......:
  Rat   383 GLRKDFDLDI-ISLKEEGTEKASGEVSKHLYKVWK------------KIGIWNSNSGLNMTDGNR 434

  Fly   211 NTWVIRRRN----FLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERMF 271
            :    |..|    ..|.|||.:|:| |:|    .:.|...||.|...|..:.....|.:.:..:.
  Rat   435 D----RSNNITDSLANRTLIVTTIL-EEP----YVMYRKSDKPLYGNDRFEGYCLDLLKELSNIL 490

  Fly   272 NLSLAISLT--DKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHF 334
            .....:.|.  .|:|...|.|.|:|::.::....||.||.|:.....|:..:.:|....|..|..
  Rat   491 GFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISI 555

  Fly   335 LFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM-----------LSNMENR 387
            |:|.|..::.... |..|||..:|..||....|.:.:|....|....           ...:||.
  Rat   556 LYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENN 620

  Fly   388 FSFV---WFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSI 448
            |:.:   ||. :...:|||  :|:. :..|||::..:...|:.:::..|.|.:...|..|...|.
  Rat   621 FTLLNSFWFG-VGALMQQG--SELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESP 682

  Fly   449 VNLQALYDS--NLAIGMENISYNFPIFTNTSNQLVRD----VYVKKICKSGEHNI---MSLQQGA 504
            :      ||  :|| ....|.|.          .|||    .:.||...|....:   ||.:|.:
  Rat   683 I------DSADDLA-KQTKIEYG----------AVRDGSTMTFFKKSKISTYEKMWAFMSSRQQS 730

  Fly   505 ERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEV---MFNLPYDSGSVMPKGSPWREHL 563
            ..:..........:...|.||:|   ::......|:|.::   :.:..|..|:  |.|||:|:.:
  Rat   731 ALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGT--PIGSPYRDKI 793

  Fly   564 AHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE-VDLEHFAPALFALALAMVASALVFLLEL 627
            ..|:|..:..|.|....:||. |...|....:.:|. :.:|:.......||..:|.|..|.:.|
  Rat   794 TIAILQLQEEGKLHMMKEKWW-RGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGE- 856

  Fly   628 FLH 630
            ||:
  Rat   857 FLY 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	22/73 (30%)
		Lig_chan	353..602	CDD:459656	62/279 (22%)
Grik1	NP_001104587.1	PBP1_iGluR_Kainate	38..431	CDD:380605	15/60 (25%)
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:473866	95/396 (24%)