Protein Alignment Ir84a and Grik5

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 698
• Identity: 153/698 - (21%)
• Similarity: 272/698 - (38%)
• Gaps: 191/698 - (27%)

  Fly    14 IILTAFLRVLQIESI---NTNFLELAAFE-------DFLRSEHLSHVLVVRGDDADGDWKIECHQ 68
            |:.|....:|.::.|   ::|.|..:.|.       :|:||.::|             |:..|
Mouse   266 ILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMS-------------WRENC-- 315

  Fly    69 KLLANYRVQFYRPEMSANFEDLMFYGSPRTAVLVLNSEHVLV-------RRQVFGV--------- 117
                               |...:.|...:|.|:.::.||:|       |.|..||
Mouse   316 -------------------EASTYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSAN 361

  Fly   118 -----ASEAGY--------------FNNSLAWFILGSGRESLPVEQLIDQLLSGYR-MGI-DADI 161
                 .|...|              ||:        .|:.:....:::::...|:| :|: .::.
Mouse   362 IWPHGTSLMNYLRMVEYDGLTGRVEFNS--------KGQRTNYTLRILEKSRQGHREIGVWYSNR 418

  Fly   162 TVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTLI 226
            |:|:    ||:.|  |:......||..|::..              ..:|.:|:||.||  ..|.
Mouse   419 TLAM----NATTL--DINLSQTLANKTLVVTT--------------ILENPYVMRRPNF--QALS 461

  Fly   227 GSTVLTEKPPGF-GDMEYLADDKQLQQLDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDNG 290
            |:    |:..|| .||        |::|..:.|..|:| :|||           ...:|....||
Mouse   462 GN----ERFEGFCVDM--------LRELAELLRFRYRL-RLVE-----------DGLYGAPEPNG 502

  Fly   291 SWSGVMGQVTSRE-ADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFR-HPRRSHIKNIFFEPLS 353
            ||:|::|::.:|: ||.||.......:|:..:.:|....|..|..|:| |..|......|.:|.|
Mouse   503 SWTGMVGELINRQKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFS 567

  Fly   354 NQVW-WCVLALVTGSTILLLF-----------HVRLERMLSNMENRFSF---VWFTMLETYLQQG 403
            ..|| :.:||.:..|.:|.|.           |..|......:||:::.   :||. :..::|||
Mouse   568 PAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFP-VGGFMQQG 631

  Fly   404 PANEIF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSLL-------SESARSIVNLQALYDSNLA 460
              :||. |..|||.:..:...|:.:::..|.|.:...|.       .|||..:.:     .:|:.
Mouse   632 --SEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLAD-----QTNIE 689

  Fly   461 IGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLL 525
            .|..:.......|.|:..|..:.::.....|.....:.|.::|..|::..|:||          |
Mouse   690 YGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAF----------L 744

  Fly   526 LELQMDEAE---FCDLQEV---MFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWM 584
            ||..|:|..   .|:|.::   :....|..|  ||.|||:|:.:..|:|..:....|:...:||.
Mouse   745 LESTMNEYHRRLNCNLTQIGGLLDTKGYGIG--MPLGSPFRDEITLAILQLQENNRLEILKRKWW 807

  Fly   585 VRRPDCSLFKTSQAE-VDLEHFAPALFALALAMVASALVFLLELFLHW 631
             ....|...:..:|: :.:|:.......|...::.:..|.::|..  |
Mouse   808 -EGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFI--W 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	9/64 (14%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	23/74 (31%)
		Lig_chan	353..602	CDD:459656	64/278 (23%)
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	34/203 (17%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:473866	107/431 (25%)