Protein Alignment Ir84a and Grik4

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_780690.2
• Gene: Grik4 / 110637
• MGIID: 95817
• Length: 956
• Species: Mus musculus
• Alignment Length: 715
• Identity: 146/715 - (20%)
• Similarity: 265/715 - (37%)
• Gaps: 199/715 - (27%)

  Fly    63 KIEC---HQKLLANYRVQFYRPEMSANFED--------LMFYGSPRTAVLVLN-----SEHVLVR 111
            |.||   .:|||..:.:.  :..:|....|        |......:||.::::     |..:|::
Mouse   168 KAECLLNLEKLLRQFLIS--KDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLK 230

  Fly   112 RQVFGVASE--------------------------AGY--FNNSLAWFILGSGRESLPVEQLIDQ 148
            ....|:.|.                          .|:  ||.|.|:|           ::....
Mouse   231 AAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFF-----------QEFSQS 284

  Fly   149 LLSGYRMGIDADITVALRGPDNASMLFYD--------VYRISR-----------------QANTP 188
            |...::...|   .|...||..:|.|.:|        |..::|                 |..|.
Mouse   285 LNQSWQENCD---HVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTS 346

  Fly   189 L-----IIEKKGLWTH--------------------SGGYQKFGNFKNTWVIRR----------- 217
            |     ::|.:||..|                    ..|:|:.|.    |.:..
Mouse   347 LMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFQQIGQ----WHVAEGLSMDSRLYAS 407

  Fly   218 ---RNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLF------QLVERM-FN 272
               .:..|.||:.:|:| |.|       ||......|:::...|  |:.|      :|.|.: ||
Mouse   408 NISDSLFNTTLVVTTIL-ENP-------YLMLKGNHQEMEGNDR--YEGFCVDMLKELAEILRFN 462

  Fly   273 LSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFR 337
            ..:.:.....:|....||:|:|::|::.:|:||.||..:....:|:..:.:|....|..|..|:|
Mouse   463 YKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYR 527

  Fly   338 -HPRRSHIKNIFFEPLSNQVW-WCVLALVTGSTILLLF-----------HVRLERMLSNMENRFS 389
             |..|......|.:|.|..|| :.:||.:..|.:|.|.           |...:...:.:.|::|
Mouse   528 VHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYS 592

  Fly   390 F---VWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARS 447
            .   :||. :..::|||    |     |..|||.:..:...|:.:::..|.|.:...|..:  |.
Mouse   593 LGNSLWFP-VGGFMQQGSTIAP-----RALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQ--RM 649

  Fly   448 IVNLQALYD----SNLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHNIMSLQQGAERII 508
            .|.::::.|    :.:..|..:...:...|.|:..|..:.::.....|.....:.|.::|..|::
Mouse   650 EVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVL 714

  Fly   509 QGRFAFHTAIDRMYRLLLELQMDE---AEFCDLQEV---MFNLPYDSGSVMPKGSPWREHLAHAL 567
            ...:||          |||..|:|   ...|:|.::   :....|..|  ||.||.:|:....|:
Mouse   715 NSNYAF----------LLESTMNEYYRQRNCNLTQIGGLLDTKGYGIG--MPVGSVFRDEFDLAI 767

  Fly   568 LHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE-VDLEHFAPALFALALAMVASALVFLLELFLHW 631
            |..:....|:...:||. ....|...:..:|: :.:|:.......|...::.:..:.:|| || |
Mouse   768 LQLQENNRLEILKRKWW-EGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLE-FL-W 829

  Fly   632  631
            Mouse   830  829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	13/64 (20%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	22/73 (30%)
		Lig_chan	353..602	CDD:459656	59/278 (21%)
Grik4	NP_780690.2	Periplasmic_Binding_Protein_type1	24..402	CDD:471960	42/253 (17%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	95/400 (24%)
		QRL_CxxC_CxxC	863..927	CDD:469521
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956