Protein Alignment Ir84a and grik3

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_031752773.1
• Gene: grik3 / 100498426
• XenbaseID: XB-GENE-6050069
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 674
• Identity: 143/674 - (21%)
• Similarity: 250/674 - (37%)
• Gaps: 150/674 - (22%)

  Fly    14 IILTAFLRVLQIESINTNFLELAAFEDF-LRSEHLSHVLVVRGDDADGDWKIECHQKLLANYRVQ 77
            |..|..|..|.:|....:.:.|..|... :.:.::|.::        ..|.:|.||..
 Frog   258 IFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPYVSSIV--------DKWSMERHQAT------- 307

  Fly    78 FYRPEMSANFEDLMFYGSPRTAVLVLNSEHVL----VRRQVFGVAS------EAGYFNNSLAWFI 132
             .:|| |...:.:|    ...|.|..::.|::    .|.....|.|      :|..|.:....||
 Frog   308 -PKPE-SGLLDGIM----TTDAALTYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGSRFMNFI 366

  Fly   133 LGSGRESLPVEQLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLW 197
            ..:..|.| ..:::....||.|...|.|| ::|:...                     :||.|.|
 Frog   367 KEAQWEGL-TGRIVFNKTSGLRTDFDLDI-ISLKEDG---------------------LEKVGTW 408

  Fly   198 THSGGYQKFGNFKNTWVIRRRN----FLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQR 258
            ..|.|.    |...|...|..|    ..|.|||.:||| |:|    .:.:...|..|...|..:.
 Frog   409 NPSDGL----NITETARGRGPNISESLTNRTLIVTTVL-EEP----YVMFKRSDTPLFGKDRFEG 464

  Fly   259 KTYQLFQLVERMFNLSLAISLTD--KWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYV 321
            ....|.:.:..:......|.|.:  |:|...:.|.|:|::.::...:||.||.|:.....|:..:
 Frog   465 FCIDLLKKIAEILGFDYDIRLVEDAKYGSQDEKGQWNGLVKELIDHKADLAVAPLTITHVREKVI 529

  Fly   322 QYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM----- 380
            .:|....|..|..|:|....:..... |..|||..:|..:|....|.:.:|....|....
 Frog   530 DFSKPFMTLGISILYRKANGTAPSVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYDA 594

  Fly   381 ------LSNMENRFSFV---WFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYGAF 435
                  ...:||.|:.:   ||. :...:|||  :|:. :..|||::..:...|:.:::..|.|.
 Frog   595 HPCNPGTDVVENNFTLLNSFWFA-VGALMQQG--SELMPKALSTRIIGGIWWFFTLIIISSYTAN 656

  Fly   436 IVGSLLSESARSIVNLQALYDS--NLAIGMENISYNFPIFTNTSNQLVRDVYVKK---------- 488
            :...|..|...|.:      ||  :|| ....|.|...:...|.|      :.||
 Frog   657 LAAFLTVERMESAI------DSADDLA-KQTKIEYGAVVDGATMN------FFKKSHISTFEKMW 708

  Fly   489 ---------ICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEV 541
                     :.||.|       :|.:|::...:|          ||:|   ::......|:|.::
 Frog   709 AFMSSRPSALVKSNE-------EGIQRVLSADYA----------LLMESTAIEYITQRNCNLTQI 756

  Fly   542 ---MFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE-VDL 602
               :.:..|..|:  |.|||:|:.::.|:|..:....:....::|. |...|...|..:|. :.:
 Frog   757 GGLIDSKGYGIGT--PMGSPYRDRISIAILQLQEADEIHKMKERWW-RSGGCPEEKNKEASALGI 818

  Fly   603 EHFAPALFALALAMVASALVFLLE 626
            ::.......||..::.|.:|.:.|
 Frog   819 QNMGGIFIVLAGGLILSVVVAMAE 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	11/61 (18%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	20/73 (27%)
		Lig_chan	353..602	CDD:459656	59/291 (20%)
grik3	XP_031752773.1	PBP1_iGluR_Kainate	37..417	CDD:380605	42/206 (20%)
		Periplasmic_Binding_Protein_Type_2	433..801	CDD:473866	89/408 (22%)