Protein Alignment Ir84a and grik5

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 686
• Identity: 149/686 - (21%)
• Similarity: 263/686 - (38%)
• Gaps: 176/686 - (25%)

  Fly    14 IILTAFLRVLQIESI---NTNFLELAAFE-------DFLRSEHLSHVLVVRGDDADGDWKIECHQ 68
            |:.|....:|.:|.|   .:|.|..:.:.       :||||.::|             |:..|
 Frog   247 ILTTMDFPLLSLEGIVSDQSNILGFSMYNSSHPFYLEFLRSLNMS-------------WRENC-- 296

  Fly    69 KLLANYRVQFYRPEMSANFEDLMFYGSPRTAVLVLNSEHVLV-------RRQVFGVASEAGYFNN 126
                         |:|.      :.|...:|.|:.::.||:|       |.|..||...:  .:.
 Frog   297 -------------ELST------YLGPALSAALMFDAVHVVVSAVRELNRSQEIGVKQLS--CST 340

  Fly   127 SLAWFILGSGRESLPVEQLIDQLLSGYRM----GIDADITVALRGPDNASMLFYDVYRISRQANT 187
            |..|             |....|::..||    |:...:....:|              .|...|
 Frog   341 SQIW-------------QHGTSLMNYLRMVEYDGLTGRVEFNSKG--------------QRTNYT 378

  Fly   188 PLIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNV--------------TLIGSTVLTEKPPGF 238
            ..|:||.|     .|:::.|    .|...|...:|.              ||:.:|:| |.|...
 Frog   379 LRILEKAG-----DGHREIG----VWYSNRTLAMNATSLDLSTSETLENKTLVVTTIL-ENPYMM 433

  Fly   239 GDMEY--LADDKQ--------LQQLDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDNGSWS 293
            ....|  |:.:.|        |.:|..:.|..|:: :|||           ...:|....||||:
 Frog   434 RKSNYRSLSGNDQYEGFCAEMLMELAALLRFNYKI-KLVE-----------DGLYGAPEPNGSWT 486

  Fly   294 GVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFR-HPRRSHIKNIFFEPLSNQVW 357
            |::|::.:|:||.||.......:|:..:.:|....|..|..|:| ...|......|.:|.|..||
 Frog   487 GMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGRKPGYFSFLDPFSPAVW 551

  Fly   358 -WCVLALVTGSTILLLF-----------HVRLERMLSNMENRFSF---VWFTMLETYLQQGPANE 407
             :.:||.:..|.:|.|.           |..|......:||:::.   :||. :..::|||  :|
 Frog   552 LFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFP-VGGFMQQG--SE 613

  Fly   408 IF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYD----SNLAIGMENIS 467
            :. |..|||.:..:...|:.:::..|.|.:...|..:  |..|.:::..|    :|:..|..:..
 Frog   614 VMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQ--RMEVPIESADDLADQTNIEYGTIHGG 676

  Fly   468 YNFPIFTNTSNQLVRDVYVKKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDE 532
            .....|.|:..|..:.::.....|.....:.|.::|..|::..|:||          |||..|:|
 Frog   677 STMTFFQNSRYQTYQRMWNYMNSKQPSVFVKSTEEGIARVLNSRYAF----------LLESTMNE 731

  Fly   533 AE---FCDLQEV---MFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCS 591
            ..   .|:|.::   :....|..|  ||.|||:|:.:..|:|..:....|:...:||. ....|.
 Frog   732 YHRRLNCNLTQIGGLLDTKGYGIG--MPLGSPYRDEITLAILQLQENNRLEILKRKWW-EGGKCP 793

  Fly   592 LFKTSQAE-VDLEHFAPALFALALAMVASALVFLLE 626
            ..:..:|: :.:|:.......|...::.:..|.::|
 Frog   794 KEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAIME 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	10/64 (16%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	22/73 (30%)
		Lig_chan	353..602	CDD:459656	63/275 (23%)
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	44/229 (19%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	98/400 (25%)