Protein Alignment Ir84a and grin3b

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 825
• Identity: 150/825 - (18%)
• Similarity: 274/825 - (33%)
• Gaps: 249/825 - (30%)

  Fly     8 VISWPLIILTAFLRVLQIESINTNFLELAAFEDFLRSEHL--------SHVLVVRGDDAD----- 59
            |:::|    .|...:||:|.: ::|||: .|...|..|.:        .|:.:......:
 Frog   103 VLAFP----QAQEELLQLEFL-SSFLEI-PFISILEQEQIVPLATKNPFHLQMDTQSSVENLMDI 161

  Fly    60 -------GDWK----IECH-------QKLLANYRVQFYR--------------PEMSANFEDLMF 92
                   ..|:    |.||       |:.|.:......|              |.:..:||.:.
 Frog   162 FFSVLQNSSWEEVDIITCHPWDSASIQRYLTSNTTLVSRTILNIHPVDESALVPFLQQHFESMK- 225

  Fly    93 YGSPRTAVLVLNSEHVLVRRQ--VFGVASEAGYFNNSLAWFI------------------LGSGR 137
              :|:..:|:...:   .||.  ||.||.:.|...:...|.|                  |..|.
 Frog   226 --NPQFPMLLYGCD---ARRSSLVFRVARDCGLEAHEFHWMIGHPLNGEEMTTEGMPPGLLAYGE 285

  Fly   138 ESLP-VEQLIDQLLSGYRMGIDADITVALRGPD-----------------NASMLFYDVYRISR- 183
            .|.| :|:.|...:......|.|.:.|.   ||                 |.|...|    :||
 Frog   286 VSRPTMEKFIRDAVGLVTRAISAAVHVR---PDLALIQSMVNCNDKQTKQNESSGSY----LSRF 343

  Fly   184 QANT-------------------------PLIIEKKG--LWTHSGGYQ--KFGNFKNTWVIR--- 216
            .|||                         .|:.:..|  .|...||::  |....:..|..|
 Frog   344 LANTSFSGQTGQIYVSNNLIHTEHHYRIWSLVRDSLGDPTWVTVGGWRQGKMEVEEGLWQSRIQQ 408

  Fly   217 ---------RRNFLNVTLIGSTVLTEKPPGFGDMEYLAD--------------------DKQLQQ 252
                     |.....|||:      |.|..| ..|..||                    |...::
 Frog   409 WEPAPGGFARTKLRVVTLV------EHPFVF-TREVDADGSCPAGQMCLDPRTNNSAVLDVLFEE 466

  Fly   253 LD------PMQRKTY---QLFQLVERM-----FNLSLAISLTDKWGELLDNGSWSGVMGQVTSRE 303
            |:      |::.||.   ....|:|::     |:..|.|....|:| ......|:|::|.:.|..
 Frog   467 LNSPNGSVPLEYKTCCYGYCIDLLEKLSEDLRFDFELYIVGDGKYG-ARKGDRWTGLVGDLLSGA 530

  Fly   304 ADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVWWCVLALVTGST 368
            |..||........|...:.:::..::.::..|.|....:.....|..||...:|..:...:..:.
 Frog   531 AHMAVTSFSINSARSTVIDFTSPFYSTSLGILVRMRDTASPIGAFMWPLHWSMWVGIFVALHITA 595

  Fly   369 ILLLF-----------HVRLERMLSNMENRFSFVWFTML-ETYLQQGPANEIFRLFSTRLLISLS 421
            :.|.|           |.|....:.:..:..:..:..:. .|...:.|     :..:.|:|::|.
 Frog   596 LFLTFYEWKSPFGMTPHGRNRTKIFSYSSALNLCYAILFGRTVSSKTP-----KCCTGRVLMNLW 655

  Fly   422 CIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYV 486
            .||..:::..|.|.:...::.:  ::...|..::|..|....:...:. .::.:::.|     |:
 Frog   656 AIFCLLVLSSYTANLAAVMVGD--KTFEALSGIHDPKLHHPSQGFRFG-TVWESSAEQ-----YI 712

  Fly   487 KKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRL---------------LLELQMDEAEFC 536
            ||.... .||.|.           :|:.....|.::.|               ||:.::.....|
 Frog   713 KKSFPE-MHNYMR-----------KFSVPATSDGVHLLKTDPPTLNAFIMDKALLDYEVSIDSDC 765

  Fly   537 DLQEVMFNLPY---DSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCS---LFKT 595
            .|  :....|:   ..|..:|:.||...:::..:..::::|.:.....||....| |.   ...|
 Frog   766 KL--LTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMDTLHDKWYKMVP-CGKRVYAVT 827

  Fly   596 SQAEVDLEHFAPALFALALAMVASALVFLLELFLHW--LPDFRRR 638
            ...::.:.||:.....|.:....|.|..|:|..::.  ||..|||
 Frog   828 ETLQMGIYHFSGLFVLLCIGFCGSLLTSLMERVVYHLILPRIRRR 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	12/94 (13%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	15/72 (21%)
		Lig_chan	353..602	CDD:459656	42/281 (15%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	59/317 (19%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	73/430 (17%)
		Lig_chan	580..847	CDD:459656	45/294 (15%)