Protein Alignment Ir84a and grin2b

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_017948700.2
• Gene: grin2b / 100490580
• XenbaseID: XB-GENE-949327
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 735
• Identity: 131/735 - (17%)
• Similarity: 247/735 - (33%)
• Gaps: 191/735 - (25%)

  Fly    28 INTNFLELAAFEDFLRSE--------HLSHVLVVRGDDADGDWKIECHQKLLANYRVQFYRPEMS 84
            :.|.|.....||:.:||.        .|..|:.:.....|.|.||:...|.|.:..:..|..:..
 Frog   167 VTTYFPGYQDFENKVRSTIENSFVGWELEEVIHLDMSLDDNDSKIQNQLKKLQSPVILLYCTKEE 231

  Fly    85 ANFEDLMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFI---LGSGRESLPVE--- 143
            |.:                          :|.||...|.......|.:   :....:::|.|
 Frog   232 ATY--------------------------IFEVAHSVGLTGYGYTWIVPSLVAGDTDTVPAEFPT 270

  Fly   144 QLID--------QLLSGYRMGIDADITVALRG--------PDNASMLF-------YDVYRISRQA 185
            .||.        .|.:..|.|| |.||.|...        |.:.|..:       |:.:.:.|..
 Frog   271 GLISVSYDEWDYDLPARVRDGI-AIITTAASTMLSEHNSIPQSKSSCYNIQESRVYEAHMLKRYL 334

  Fly   186 NTPLIIEKKGLWTHSGGYQ-----------------KFGNFKN--------TWVI---------R 216
             ..:..|.:.|.....|||                 :.|.:|:        .|.:         .
 Frog   335 -INVTFEGRNLSFSEDGYQMHPKLVIILLNQQRKWERVGKYKDRSLKMKYYVWPVFELYPNSEEH 398

  Fly   217 RRNFLNVTLIGST--VLTEKPPGFGDMEYLADD---------KQLQQLDPMQRKTYQLFQLVER- 269
            :...|::..:...  |:.|      |::.|:..         ||::    .:.:|.:....::|
 Frog   399 KDEHLSIVTLEEAPFVIVE------DVDPLSGTCMRNTVPCRKQIR----TENRTEEGGNYIKRC 453

  Fly   270 ----------------MFNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQ 318
                            .|...|.:....|.|:.: ||:|:|::|:|.::.|..||..:....:|.
 Frog   454 CKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI-NGTWNGMIGEVVTKRAYMAVGSLTINEERS 517

  Fly   319 PYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVW--WCVLALVTGSTILLLFH----VRL 377
            ..|.:|.......|..:......:...:.|.||.|..||  ..|:.|:..:..:.:|.    |..
 Frog   518 EVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGY 582

  Fly   378 ERMLSN----------MENRFSFVWFTMLETYLQ-QGPANEIFRLFSTRLLISLSCIFSFMLMQF 431
            .|.|::          :......:|..:....:. |.|...     ::::::|:...|:.:.:..
 Frog   583 NRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGT-----TSKIMVSVWAFFAVIFLAS 642

  Fly   432 YGAFIVGSLLSE------SARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQL-VRDVYVKKI 489
            |.|.:...::.|      |..|....|...|.:.|       :.|....|.|.:. :|:.|::..
 Frog   643 YTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPA-------FRFGTVPNGSTERNIRNNYLEMH 700

  Fly   490 CKSGEHNIMSLQQGAERIIQGR---FAFHTAIDRMYRLLLELQMDEAEFCDL-----QEVMFNLP 546
            ....:.|..|:|.....:..|:   |.:..|:       |.......|.|.|     .:|.....
 Frog   701 SYMVKFNQRSVQDALLSLKTGKLDAFIYDAAV-------LNYMAGRDEGCKLVTIGSGKVFATTG 758

  Fly   547 YDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPALFA 611
            |  |..:.|.|.|:..:..|:|.....|.::..:..|:.........:...:::|:::.|...:.
 Frog   759 Y--GIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYM 821

  Fly   612 LALAMVASALVFLLELFLHW 631
            ||.||..|.:.|::|....|
 Frog   822 LAAAMALSLITFIMEHLFFW 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	8/57 (14%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/72 (26%)
		Lig_chan	353..602	CDD:459656	47/280 (17%)
grin2b	XP_017948700.2	PBP1_iGluR_NMDA_NR2	28..383	CDD:380601	44/243 (18%)
		PBP2_iGluR_NMDA_Nr2	400..800	CDD:270436	76/431 (18%)
		NMDAR2_C	837..1449	CDD:463148	1/5 (20%)