Protein Alignment Ir84a and grik3

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 730
• Identity: 146/730 - (20%)
• Similarity: 269/730 - (36%)
• Gaps: 165/730 - (22%)

  Fly     1 MIKLQVKVISWPLIILTAFLRVLQIESINTNFL--ELAAFEDFLRSEHLSHVLVVRGDDADGDWK 63
            :|:||..:::.....:...:|.|.:::::|..|  |:....:|......||.:..:
Zfish   179 LIRLQELIMAPSRYNIRLKIRQLPMDTVDTRPLLKEMKRSREFRIIFDCSHTMAAQ--------- 234

  Fly    64 IECHQKLLANYRVQFYR------PEMSANFEDLMFYGSPRTAVLVLNSEHVLV---------RRQ 113
             ...|..:.....::|.      ..|:.|.|...|.|...|...:||.::..|         .||
Zfish   235 -ILKQAQMMGMMTEYYHYIFTTLDLMAINLEPYRFCGVNMTGFRILNVDNPQVASIVEKWSLERQ 298

  Fly   114 V---------FGVAS-------------EAGYFN------NSL------AW--------FILGSG 136
            :         .|:.:             ...|.:      |||      .|        ||..|.
Zfish   299 IPPKPDSGLLEGIMTTDAALTYDAVHIVSVSYQHAPQMTVNSLQCHRHKPWRFGGRFMSFIKESH 363

  Fly   137 RESLPVEQLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSG 201
            .:.| ..:|.....:|.|...|.|| |:|:...                     ::|.|.|:.||
Zfish   364 WDGL-TGRLCFNRTTGLRTDFDLDI-VSLKEDG---------------------LQKVGKWSASG 405

  Fly   202 GYQKFGNFKNTWVIRRRNFLNVT-------LIGSTVLTEKPPGFGDMEYL---ADDKQLQQLDPM 256
            |.       |...:.|:|.:|:|       |:.:|:| |:|       |:   ..||.|...|..
Zfish   406 GL-------NITEVPRQNGMNITDSLSNRSLVITTIL-EEP-------YVMLKKSDKALVGNDRF 455

  Fly   257 QRKTYQLFQLVERMFNLSLAISLT--DKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQP 319
            :.....|.:.:..:...|..|.|.  .|:|...|.|.|:|::.::....||.||.|:.....|:.
Zfish   456 EGFCIDLLKELASILGFSYEIHLVPDGKYGFQDDKGQWNGMIRELMEHRADLAVAPLTITFMREK 520

  Fly   320 YVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM--- 380
            .:.:|.......|..|:|.|..::.... |..|::..:|..:|....|.:.:|....|....
Zfish   521 AIDFSKPFLNTGISILYRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIARFSPYEWY 585

  Fly   381 --------LSNMENRFSFV---WFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYG 433
                    ...:||.|:.:   ||. :.:.:|||  :|:. :..|||::..:...|:.:::..|.
Zfish   586 DAHPCNPGSDVVENNFTLLNSFWFG-VGSLMQQG--SELMPKALSTRIIGGIWWFFTLIIISSYT 647

  Fly   434 AFIVGSLLSESARSIVNL--QALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHN 496
            |.:...|..|...|.|:.  .....:.:..|:.........|..:.......::.....:.....
Zfish   648 ANLAAFLTVERMDSPVDSADDLAKQTKIEYGVVKDGATMSFFKKSRVSTFEKMWAFMSSRQSTSF 712

  Fly   497 IMSLQQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEV---MFNLPYDSGSVMPK 555
            :.|::.|.:|:::..:|          ||:|   ::......|:|.:|   :.:..|..|:  ||
Zfish   713 VKSIEDGIQRVLKSDYA----------LLMESTTIEYVTRRNCNLTQVGGIIDSKGYGIGT--PK 765

  Fly   556 GSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE---VDLEHFAPALFALALAMV 617
            |||:|:.:..|:|.....|.|....:||.   ...|..:..:.|   :.:::.......||..:|
Zfish   766 GSPYRDKITIAILGILEDGRLHMLKEKWW---SGSSCLEDERYETGPMGIQNLGGIFIVLASGLV 827

  Fly   618 ASALVFLLELFLHWL 632
            .|..|.:.| |::.|
Zfish   828 LSVFVAIGE-FIYKL 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	11/72 (15%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/73 (26%)
		Lig_chan	353..602	CDD:459656	52/274 (19%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	49/270 (18%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	82/390 (21%)