Protein Alignment Ir84a and grin2db

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_073782035.1
• Gene: grin2db / 100149482
• ZFINID: ZDB-GENE-100920-7
• Length: 1984
• Species: Danio rerio
• Alignment Length: 670
• Identity: 137/670 - (20%)
• Similarity: 233/670 - (34%)
• Gaps: 170/670 - (25%)

  Fly    94 GSPRTAVLVLNSEHVLVR---------RQVFGVASEAGYFNNSLAWFILGSGRESLPVEQLIDQL 149
            |..||..|:..:| ..||         .|||..|..||....|..||.:|.....|.:..|..:|
Zfish   266 GGVRTQRLLKENE-AQVRLLYCSQEEAEQVFLAAWAAGQAGASHIWFAVGPALSELGLTGLPKRL 329

  Fly   150 LS----GYR----------MGIDADITVALR-------GPDNASMLFYDVYRISR---------- 183
            .:    |:|          :.|.....||||       ||...:....|..|..|
Zfish   330 FAVRPQGWRDEPRRRIARGVSILTHGAVALRKDYGATGGPHFVTNCQTDGNRTQRIRGRMRYFSN 394

  Fly   184 ---------------QANTPLIIEKKGLWTHSGGYQKFGNFKN--------TW------------ 213
                           .||..|.:..   :|...|::..|.::|        .|
Zfish   395 ITLGGRDYSFSNEGYLANPFLDVIS---YTPGSGWEDVGWWENGVLRLRYPAWSRYGPFLQPPDD 456

  Fly   214 -------VIRRRNFLNV--------TLIGSTVLTEKPPGFGDM-EYLADDKQLQQ---LDPMQRK 259
                   .:..|.|:.|        |.|..:|...:|.....: |.:|..||..:   :|.::|
Zfish   457 AQHLRVVTLEERPFVIVELADAASGTCIRDSVPCRRPLNASALQEGVAPVKQCCKGFCIDILKR- 520

  Fly   260 TYQLFQLVERMFNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYS 324
               |.::|.  |...|.:....|.|:.:| |.|:|::|:|..:.||.|:..:....:|...|.:|
Zfish   521 ---LARIVG--FTYDLYLVTNGKHGKKID-GVWNGMVGEVVYKRADMAIGSLTINEERSEVVDFS 579

  Fly   325 AVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVW--WCVLALVTGSTILLLFH----VRLERMLSN 383
            .......|..:......:...:.|.||.|..||  ..|:.|...:..:.:|.    |...|.|.:
Zfish   580 VPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEFFSPVGYNRSLQS 644

  Fly   384 ME----NRFSF---VWFTMLETYLQQGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLL 441
            .:    ::|:.   :|......:....|. |..:..::::::.:...|:.:.:..|.|.:...::
Zfish   645 GKKAGGSKFTIGKSIWLLWALVFNNSVPV-ENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMI 708

  Fly   442 SESARSIVNLQALYDSN----------LAIGM-------ENISYNFPIFTNTSNQLVRDVY---V 486
            .|  ..|..:..|.|..          |..|.       :||..|:|           |::   |
Zfish   709 QE--EYIDTVSGLSDKKFQHPTEQYPPLKFGTVPNGSTEKNIRSNYP-----------DMHQYMV 760

  Fly   487 KKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDEAEFCDLQ-----EVMFNLP 546
            |...||.|..|..|:.|.    ...|.:..|:       |.....:.|.|.:.     :|.....
Zfish   761 KYNQKSVEDAISHLKTGK----LDAFIYDAAV-------LNYMARKDEGCKVMTIGSGKVFATTG 814

  Fly   547 YDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPALFA 611
            |  |..:.|.|.|:..|..|||.......::..::.|:.........:...:::|:::.|...:.
Zfish   815 Y--GIALIKNSRWKRPLDLALLQLVGDDEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVFYM 877

  Fly   612 LALAMVASALVFLLELFLHW 631
            |.:||..|.|||..|..::|
Zfish   878 LLVAMGLSLLVFAWEHLVYW 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	7/26 (27%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/72 (26%)
		Lig_chan	353..602	CDD:459656	51/286 (18%)
grin2db	XP_073782035.1	None