DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1227 and Gm7358

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_978062.3	Gene:	Gm7358 / 664831	MGIID:	3643256	Length:	549	Species:	Mus musculus

Alignment Length:	280	Identity:	64/280 - (22%)
Similarity:	124/280 - (44%)	Gaps:	33/280 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRYTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVD 92
            |:|.:...|..|.::.:.|.::..|....|:|.:..:....|. |::|....:||...|::.::.
Mouse    67 SQYKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQP-AMKEANIMKKIKHPNIVSLLQ 130

  Fly    93 YELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEA 157
                     ||.|.:..::::...:...|.:::    :...|:.|.:..||||.:...:...|.:
Mouse   131 ---------VIETKTRGYLIMELVEGQELYEYI----KNSGHIEEDEARQIFLQILSAVGYCHGS 182

  Fly   158 MPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELF 222
               .:.|||||..||.:.......|:|.|..|:.:       ..|.|.   |...:..:.|||||
Mouse   183 ---GIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVK-------PGQLLH---EHCGAYAFGAPELF 234

  Fly   223 TVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHEL 287
            ..|:|  ...::|:|:||.:||.|.....|:|....  ..:.:.:|:|  ..|.....:.::.:|
Mouse   235 LWKSY--DGTKSDLWALGVILYYMVVGKVPFDSFII--PELQMQILAG--VYPAPCGVSNELKDL 293

  Fly   288 IKYMLRTDPMERPFVFSVIE 307
            :..::..:|..||.|..|::
Mouse   294 LSLLMTVNPKYRPTVTEVMK 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	63/279 (23%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	59/269 (22%)
Gm7358	XP_978062.3	STKc_AMPK-like	68..316	CDD:270905	63/279 (23%)
Gm7358	XP_978062.3	UBA_MARK_Par1	336..375	CDD:270522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910