DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1227 and mark4b

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_005157655.1	Gene:	mark4b / 571279	ZFINID:	ZDB-GENE-100330-2	Length:	796	Species:	Danio rerio

Alignment Length:	296	Identity:	76/296 - (25%)
Similarity:	122/296 - (41%)	Gaps:	48/296 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RGCLFSCRKETLNINGSRYTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNI--ALR 74
            |..:.||..|..:|  ..|.:.:.:..|.|:.:.|..:..|.|..|||.|....::..::  ..|
Zfish    42 RNSIASCSDEQPHI--GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR 104

  Fly    75 EIENCRKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQ 139
            |:...:.::..|::::.:         ||.|..||::|:.|...|.:.|:|....|.::.....:
Zfish   105 EVRIMKGLNHPNIVQLFE---------VIETEKTLYLVMEYASGGEVFDYLVSHGRMKEKEARGK 160

  Fly   140 ILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRL 204
            ..||       :.|:|......:.|||||..|:.|.......|.|.|...|..|       ..:|
Zfish   161 FRQI-------VSAVHYCHLKNIVHRDLKAENLLLDADSNIKIADFGFSNEFTL-------GSKL 211

  Fly   205 QDEAEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYD-----PIYERGDSVA 264
            ....   .|..|.|||||..|.|  .....||||||.:||.:...:.|:|     .:.||
Zfish   212 DTFC---GSPPYAAPELFQGKKY--DGPEVDIWSLGVILYTLVSGSLPFDGQNLKELRER----- 266

  Fly   265 LAVLSGNINIPEDSIY-TEDMHELIKYMLRTDPMER 299
              ||.|...:|   .| :.|...:::..|..:|.:|
Zfish   267 --VLRGKYRVP---FYMSTDCEGILRRFLVLNPTKR 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	71/279 (25%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	71/278 (26%)
mark4b	XP_005157655.1	STKc_MARK	57..309	CDD:270974	71/279 (25%)
		S_TKc	58..309	CDD:214567	71/278 (26%)
		UBA_like_SF	327..369	CDD:304366
		MARK4_C	699..796	CDD:213382
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910