DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1227 and pak6b

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001155959.1	Gene:	pak6b / 567874	ZFINID:	ZDB-GENE-041014-121	Length:	607	Species:	Danio rerio

Alignment Length:	302	Identity:	60/302 - (19%)
Similarity:	113/302 - (37%)	Gaps:	66/302 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDYELKGQA 99
            ::..|...::.:.....:.|..|:|.:.......:.:...|:...|....:||:.:....|.|:
Zfish   338 KIGEGSTGVVCIAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYRHQNVVEMYKSALVGE- 401

  Fly   100 DIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAH 164
                    .|::::.|.:.|:|.:.:     .:..:.|.||..:...|.:.|..:|..   .:.|
Zfish   402 --------ELWVIMEYLQGGALTNIV-----SETRLTEEQIATVCESVLQALCYLHSQ---GVIH 450

  Fly   165 RDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSI---VYRAPELFTVKT 226
            ||:|:.:|.|:......:.|.|..            ||..:|..:.||.:   .:.|||:.:...
Zfish   451 RDIKSDSILLTLDGRVKLSDFGFC------------AQISKDVPKRRSLVGTPYWMAPEVVSKTP 503

  Fly   227 YCTIDERTDIWSLGCVLYAMCYFNSPY---------------DPIYERGDSVALAVLSGNINIPE 276
            |.|   ..||||||.::..|.....||               .|...|..|....||...:
Zfish   504 YGT---EVDIWSLGIMVVEMVDGEPPYFSETPISAMKRLRDEPPPTARNASKISPVLRDFL---- 561

  Fly   277 DSIYTEDMHELIKYMLRTDPMERPFVFS---------VIERT 309
            ||:.|.:..:...   .:|.::.||:..         ::|:|
Zfish   562 DSMLTREPQQRSS---ASDLLQHPFLLQCSSPRCLIPLVEQT 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	60/302 (20%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	56/282 (20%)
pak6b	NP_001155959.1	PBD	13..65	CDD:279166
		STKc_PAK6	311..607	CDD:270821	60/302 (20%)
		S_TKc	338..584	CDD:214567	57/284 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910