Protein Alignment CG1227 and NEK1

DIOPT Version :9

• Sequence 1: NP_001287207.1
• Gene: CG1227 / 40872
• FlyBaseID: FBgn0037491
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001186326.1
• Gene: NEK1 / 4750
• HGNCID: 7744
• Length: 1286
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 76/290 - (26%)
• Similarity: 136/290 - (46%)
• Gaps: 47/290 - (16%)

  Fly    29 RYTIRERLATGGFSLIDLGENASTRRSYAIKRITCH--SIDDQNIALREIENCRKIDSENVIRVV 91
            :|...:::..|.|....|.::....|.|.||.|...  |..::..:.||:.....:...|:::..
Human     3 KYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHPNIVQYR 67

  Fly    92 D-YELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIH 155
            : :|..|          :|:||:.|.:.|.|  ..::.::|.....|.|||..|:.:|..||.:|
Human    68 ESFEENG----------SLYIVMDYCEGGDL--FKRINAQKGVLFQEDQILDWFVQICLALKHVH 120

  Fly   156 EAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIV----Y 216
            :.   .:.|||:|:.||.|:   :...|.||....||:          |....|...:.:    |
Human   121 DR---KILHRDIKSQNIFLT---KDGTVQLGDFGIARV----------LNSTVELARTCIGTPYY 169

  Fly   217 RAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGD--SVALAVLSGNINIPEDSI 279
            .:||:...|.|   :.::|||:||||||.:|....    .:|.|.  ::.|.::||  :.|..|:
Human   170 LSPEICENKPY---NNKSDIWALGCVLYELCTLKH----AFEAGSMKNLVLKIISG--SFPPVSL 225

  Fly   280 -YTEDMHELIKYMLRTDPMERPFVFSVIER 308
             |:.|:..|:..:.:.:|.:||.|.|::|:
Human   226 HYSYDLRSLVSQLFKRNPRDRPSVNSILEK 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	76/290 (26%)
		S_TKc	30..300	CDD:214567	71/279 (25%)
NEK1	NP_001186326.1	STKc_Nek1	3..258	CDD:270858	76/290 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910