DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1227 and Ttk

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_006511121.1	Gene:	Ttk / 22137	MGIID:	1194921	Length:	869	Species:	Mus musculus

Alignment Length:	309	Identity:	78/309 - (25%)
Similarity:	141/309 - (45%)	Gaps:	47/309 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ETLNINGSRYTIRERLATGGFSLI--DLGENASTRRSYAIKRITCHSIDDQNIA--LREIENCRK 81
            |.:::||..|:|.:::.:||.|.:  .|.|.   ::..|||.:.....|.|.|.  ..||....|
Mouse   528 ECISVNGRIYSILKQIGSGGSSKVFQVLNEK---KQINAIKYVNLEDADSQTIESYRNEIAFLNK 589

  Fly    82 ID--SENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIF 144
            :.  |:.:||:.|||:         |...:::|:   :.|::..:..|:.:|..:..|.:  ..:
Mouse   590 LQQHSDKIIRLYDYEI---------TEQYIYMVM---ECGNIDLNSWLKKKKSINPWERK--SYW 640

  Fly   145 LGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAE 209
            ..:.|.:..||:.   .:.|.|||.||..:.|....:| |.|...:.      |.|...:..:::
Mouse   641 KNMLEAVHIIHQH---GIVHSDLKPANFVIVDGMLKLI-DFGIANQM------QPDTTSIVKDSQ 695

  Fly   210 ERSSIVYRAPELF--------TVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSV-AL 265
            . .::.|.|||..        ..|....:..|:|:|||||:||.|.|..:|:..|..:...: |:
Mouse   696 V-GTVNYMAPEAIRDMSSSRENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAI 759

  Fly   266 AVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERTHDLIQ 314
            ...:..|..||  |..:|:.:::|..|..:|.||..:..::  ||..:|
Mouse   760 INPAHEIEFPE--ISEKDLRDVLKCCLVRNPKERISIPELL--THPYVQ 804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	74/299 (25%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	71/284 (25%)
Ttk	XP_006511121.1	TPR repeat	143..172	CDD:276809
		TPR repeat	177..205	CDD:276809
		PKc_Mps1	535..803	CDD:271033	74/299 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910