DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1227 and par-1

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001122967.2	Gene:	par-1 / 179912	WormBaseID:	WBGene00003916	Length:	1216	Species:	Caenorhabditis elegans

Alignment Length:	299	Identity:	74/299 - (24%)
Similarity:	130/299 - (43%)	Gaps:	46/299 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SCRKETLNINGSRYTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNI--ALREIENC 79
            :.|:...:::..:|.:.:.:..|.|:.:.|.::..|....|||.|...:::..::  ..||::..
Worm    93 AARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIM 157

  Fly    80 RKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIF 144
            :::|..|::::  |:       |:.|..||::||.|...|.:.|:|....|.::....|:..||
Worm   158 KQLDHPNIVKL--YQ-------VMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQI- 212

  Fly   145 LGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAE 209
                  :.|:.......:.|||||..|:.|.......|.|.|......|       ..:|....
Worm   213 ------VSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSL-------GNKLDTFC- 263

  Fly   210 ERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYD-----PIYERGDSVALAVLS 269
              .|..|.|||||:.|.|  .....|:||||.:||.:...:.|:|     .:.||       ||.
Worm   264 --GSPPYAAPELFSGKKY--DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRER-------VLR 317

  Fly   270 GNINIPEDSIY-TEDMHELIKYMLRTDPMERPFVFSVIE 307
            |...||   .| :.|...|:|..|..:|..|..:.::::
Worm   318 GKYRIP---FYMSTDCENLLKKFLVINPQRRSSLDNIMK 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	73/287 (25%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	72/277 (26%)
par-1	NP_001122967.2	STKc_MARK	105..357	CDD:270974	73/287 (25%)
		S_TKc	106..357	CDD:214567	73/286 (26%)
		MARK1-3_C	1117..1214	CDD:213381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910