DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1227 and mark4

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_012824414.1	Gene:	mark4 / 100491038	XenbaseID:	XB-GENE-6042140	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	278	Identity:	71/278 - (25%)
Similarity:	115/278 - (41%)	Gaps:	46/278 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNI--ALREIENCRKIDSENVIRVVD 92
            |.:...:..|.|:.:.|..:..|.|..|||.|....::..::  ..||:...:.::..|::::.:
Frog    51 YRLLRTIGKGNFAKVKLARHVLTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFE 115

  Fly    93 YELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEA 157
                     ||.|..||::::.|...|.:.|:|....|.::....|:..||       :.|:|..
Frog   116 ---------VIETEKTLYLIMEYASGGEVFDYLVSHGRMKEKEARAKFRQI-------VSAVHYC 164

  Fly   158 MPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELF 222
            ....:.|||||..|:.|.......|.|.|...|.       |...:|....   .|..|.|||||
Frog   165 HQKNIVHRDLKAENLLLDSESNIKIADFGFSNEF-------TPGGKLDTFC---GSPPYAAPELF 219

  Fly   223 TVKTYCTIDERTDIWSLGCVLYAMCYFNSPYD-----PIYERGDSVALAVLSGNINIPEDSIY-T 281
            ..|.|  .....|:||||.:||.:...:.|:|     .:.||       ||.|...||   .| :
Frog   220 QGKRY--NGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRER-------VLRGKYRIP---FYMS 272

  Fly   282 EDMHELIKYMLRTDPMER 299
            .|...:::..|..:|.:|
Frog   273 TDCEGVLRRFLVLNPSKR 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	71/278 (26%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	71/278 (26%)
mark4	XP_012824414.1	STKc_MARK	50..302	CDD:270974	71/278 (26%)
mark4	XP_012824414.1	UBA_MARK_Par1	323..361	CDD:270522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910