DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG2656 and Gpn3

Sequence 1:NP_649699.1 Gene:CG2656 FlyBaseID:FBgn0037478 Length:283 Species:Drosophila melanogaster
Sequence 2:NP_077178.1 Gene:Gpn3 MGIID:1289326 Length:284 Species:Mus musculus

Alignment Length:282 Identity:149/283 (53%)
Similarity:201/283 (71%) Gaps:15/283 (5%)


  Fly     2 RFAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMEDE 66
            |:||:::||||||||||||.|.|:.....|:|||||||||||||.|..:.|||:||.:||.||||
Mouse     3 RYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMEDE 67

  Fly    67 ELHYGPNGGLIFCLEFLIENQEWLKEQLCGGENELMVGEPDDDYILFDMPGQIELFTHLKMGRQL 131
            .|.:||||||:||:|:...|.:||         |..:|..:|||||||.||||||:|||.:.:||
Mouse    68 SLRFGPNGGLVFCMEYFANNFDWL---------ENCLGHVEDDYILFDCPGQIELYTHLPVMKQL 123

  Fly   132 VELLESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSDARKQLE 196
            |:.||.|.||.|.||.:||||||:..|||||.:||||.|.::|.|.:|::||:||||..|:|::|
Mouse   124 VQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMVSLEIPQVNIMTKMDLLSKKAKKEIE 188

  Fly   197 MYLEPDAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLLQIDSIL 261
            .:|:||.:||:.:.| |....:|:.|||:|:..|::|:|:|||.|.|..||||:..:|..||..:
Mouse   189 KFLDPDMYSLIDDST-GDLRSQKFKKLTKAVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAI 252

  Fly   262 QYGEDADVNVKDFDEPEEGDQD 283
            |||||.     :|.||.|.:::
Mouse   253 QYGEDL-----EFKEPREHEEE 269

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG2656NP_649699.1 Gem1 2..196 CDD:224025 112/194 (58%)
ATP_bind_1 7..263 CDD:281079 138/256 (54%)
Gpn3NP_077178.1 Gem1 1..219 CDD:224025 125/226 (55%)
ATP_bind_1 8..254 CDD:281079 138/256 (54%)
Gly-Pro-Asn (GPN)-loop, involved in dimer interface. {ECO:0000250|UniProtKB:Q9UYR9} 72..74 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C8217316
eggNOG 1 0.900 E1_KOG1534
Hieranoid 1 1.000
Homologene 1 1.000 H6487
Inparanoid 1 1.050 304 1.000 Inparanoid score I2630
Isobase 1 0.950 0 Normalized mean entropy S519
OMA 1 1.010
OrthoDB 1 1.010 D432496at33208
OrthoFinder 1 1.000 FOG0004261
OrthoInspector 1 1.000 T1084274
orthoMCL 1 0.900 OOG5_128003
Panther 1 1.100 LDO PTHR21231
Phylome 1 0.910 0.667 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R521
TreeFam 1 0.960
1514.750

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