Protein Alignment CG2656 and GPN2

DIOPT Version :10

• Sequence 1: NP_649699.1
• Gene: CG2656 / 40857
• FlyBaseID: FBgn0037478
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: NP_060536.3
• Gene: GPN2 / 54707
• HGNCID: 25513
• Length: 310
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 103/265 - (38%)
• Similarity: 146/265 - (55%)
• Gaps: 17/265 - (6%)

  Fly     3 FAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMEDEE 67
            |.|.::||.||||:|||..|.::.....|.|.|||||||.|...|....|:.:|:.|.|.|  :.
Human    10 FGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVM--DA 72

  Fly    68 LHYGPNGGLIFCLEFLIENQEWLKEQLCGGENELMVGEP-DDDYILFDMPGQIELFTHLKMGRQL 131
            |..||||||::|:|:|..|.:||:.:|          :| ...|.|||.|||:||.||....|.:
Human    73 LRLGPNGGLLYCMEYLEANLDWLRAKL----------DPLRGHYFLFDCPGQVELCTHHGALRSI 127

  Fly   132 VELLESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSDARK--Q 194
            ...:..|:.|...|..:||.:..|.|||||....:|:.|.::|.||||:|:|:||:....:.  .
Human   128 FSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYGKLAFN 192

  Fly   195 LEMYLEP-DAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLLQID 258
            |:.|.|. |...|:..|. ...|...|.:|.:.:..||||:|||.|.||:.||:||:..:|..:|
Human   193 LDYYTEVLDLSYLLDHLA-SDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVD 256

  Fly   259 SILQY 263
            ....|
Human   257 KANGY 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	GPN3	3..258	CDD:349781	101/258 (39%)
GPN2	NP_060536.3	GPN2	10..257	CDD:349780	101/259 (39%)
		Gly-Pro-Asn (GPN)-loop, involved in dimer interface. /evidence=ECO:0000250|UniProtKB:Q9UYR9	76..78		1/1 (100%)