DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2656 and eIF5B

DIOPT Version :9

Sequence 1:	NP_649699.1	Gene:	CG2656 / 40857	FlyBaseID:	FBgn0037478	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001246599.1	Gene:	eIF5B / 44261	FlyBaseID:	FBgn0026259	Length:	1144	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	43/212 - (20%)
Similarity:	77/212 - (36%)	Gaps:	55/212 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 EWLKEQ------LCGGENELMVGEPDDDYILFDMPGQIELFTHLK-MGRQLVELLESWNFRTCVV 145
            |.:|||      ..|.|:.|      ...::.|.||. |.|::|: .|..|.::         .:
  Fly   600 EAIKEQTKYVKAAAGFEHRL------PGLLIIDTPGH-ESFSNLRNRGSSLCDI---------AI 648

  Fly   146 FCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLL---SSDARKQLEMYLEPDAHSLM 207
            ..:|   ::.|.:  ..|:.::.::...:.|.|..|.|:|.|   ...||:.:...|:....:..
  Fly   649 LVVD---IMHGLE--PQTIESIQLLKKKKCPFIVALNKIDRLYDWKQLARRDVRDVLKEQQSNTQ 708

  Fly   208 GELTIGT-----GFGEKYAKLTQAIGALI-----EDFSLVRFFPLDSQDEESVGDLLLQIDSI-- 260
            .|....|     .|.|      |.:.|.:     :..:.:...|..:...|.:|:||..|...
  Fly   709 LEFQQRTKDVILQFAE------QGLNAALFYENTDPKTYISLVPTSAISGEGMGNLLFMIADFCQ 767

  Fly   261 ------LQYGEDADVNV 271
                  |.|.|:....|
  Fly   768 NMLAKRLMYSEELQATV 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	Gem1	2..196	CDD:224025	26/117 (22%)
CG2656	NP_649699.1	ATP_bind_1	7..263	CDD:281079	40/202 (20%)
eIF5B	NP_001246599.1	PRK04004	553..1129	CDD:235195	43/212 (20%)
		IF2_eIF5B	557..769	CDD:206674	39/195 (20%)
		aeIF5B_II	779..889	CDD:293904	1/6 (17%)
		IF-2	890..993	CDD:288813
		IF2_aeIF5B_IV	1016..1110	CDD:293911
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910