DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2656 and Gpn2

DIOPT Version :9

Sequence 1:	NP_649699.1	Gene:	CG2656 / 40857	FlyBaseID:	FBgn0037478	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001257888.1	Gene:	Gpn2 / 362614	RGDID:	1311749	Length:	310	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	102/265 - (38%)
Similarity:	146/265 - (55%)	Gaps:	17/265 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMEDEE 67
            |.|.::||.||||:|||..|.::.....|.|.|||||||.|...|....|:.:|:.|.|.|  :.
  Rat    10 FGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVM--DA 72

  Fly    68 LHYGPNGGLIFCLEFLIENQEWLKEQLCGGENELMVGEP-DDDYILFDMPGQIELFTHLKMGRQL 131
            |..||||||::|:|:|..|.:||:.:|          || ...|.|||.|||:||.||....|.:
  Rat    73 LRLGPNGGLLYCMEYLEANLDWLRAKL----------EPLRGHYFLFDCPGQVELCTHHTSLRSI 127

  Fly   132 VELLESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSDARK--Q 194
            ...:..|:.|...|..:||.:..|.|||||....:|:.|.::|.||:|:|:|:||:....:.  .
  Rat   128 FSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYGKLAFN 192

  Fly   195 LEMYLEP-DAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLLQID 258
            |:.|.|. |...|:..|. ...|...|.:|.:.:..||||:|||.|.||:.||::|:..:|..:|
  Rat   193 LDYYTEVLDLSYLLDHLA-SDPFFSHYRQLNEKLVQLIEDYSLVSFIPLNIQDKDSIQRVLQAVD 256

  Fly   259 SILQY 263
            ....|
  Rat   257 KANGY 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	Gem1	2..196	CDD:224025	77/195 (39%)
CG2656	NP_649699.1	ATP_bind_1	7..263	CDD:281079	99/259 (38%)
Gpn2	NP_001257888.1	Gem1	13..182	CDD:224025	73/180 (41%)
		ATP_bind_1	14..261	CDD:281079	99/259 (38%)
		Gly-Pro-Asn (GPN)-loop, involved in dimer interface. /evidence=ECO:0000250\|UniProtKB:Q9UYR9	76..78		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920